Abstract 【Abstract】Objectives
To
report
an infant with central hypoventilation
syndrome
treated by non—invasive
bi—level airway pressure ventilation and review the related 1iterature．Methods Clinieal
data of an infant with
CCHS treated bv BiPAP and the related literature were collected and analyzed．Results A female infant showed
a significant
dyspnea
after birth and
obviously
ventilator impairment in sleep，with repeated weaning failure．A
PHOX2B mutation was indentified in this baby and confirmed
as CCHS．She was
supported by
non-invasive
BiPAP with normal pulse oximetry(Sp02)and transcutaneous partial pressure of carbon dioxide(TepC02)．
The infant was
discharged
home at 3 months of
age
with non—invasive BiPAP and showed normal development
after 4 months of follow up．Conclusion Non-invasive BiPAP is one of the effective methods in the treatment of
CCHS and can avoid the adverse consequences caused by tracheotomy．
2013, Vol. 1 
