Journal of Developmental Medicine(Electronic Version)  2016, Vol. 4 Issue (3): 148-152 DOI: |
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| Surgical timing and outcome of arterial switch operationfor neonates with transposition of the greatarteries with intact ventricular septum |
| WANG Hui, HONG Xiao-yang, LIU Yu-hang , et al
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| WANG Hui, HONG Xiao-yang, LIU Yu-hang, WANG Gang, CHEN Xi, XIN Cheng-lei, ZHOU Geng-xu (Department of Cardiac Surgery, Bayi Children’s Hospital Affiliated to Chinese People's Liberation Army General Hospital, Beijing 100700, China) |
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Abstract Objective To analyze the surgical timing and outcome of artery switch operation (ASO) for neonates with transposition of the great arteries with intact ventricular septum (TGA/IVS) . Methods 25 patients underwent ASO from February 2012 to February 2015 were analyzed retrospectively. There were 13 cases in group of emergency operation (group A), and 12 cases in group of selective operation (group B). The surgical outcomes of two groups were compared. Results There were 19 male cases and 6 female cases among the 25 patients. The indexes of sex ratio, proportion of premature infants, birth weight, age at hospitalization, weight at operation, age at operation and artery location of the two groups were no statistically different (P>0.05). The duration of admission to operation of group A was shorter than that of group B［1.0 (1.0~1.5) vs 1.0 (8.3~14.8) d, T=91.000, P<0.05)］. The ratio of pre-operation mechanical ventilation of group A was higher (13/13 vs 3/12, χ2=15.234, P < 0.05), while pre-operative oxygen partial pressure was lower than that of group B［23 (17~27) vs 30 (23~45) mmHg, T=127.000, P<0.05)］. Therewere no statistically difference (P>0.05) in extracorporeal circulation time, aorta blocking time and the ratio of delayed sternal closure. Meanwhile, the proportion of early low cardiac output syndrome (2/13 vs 1/12, χ2=0.294), the proportion of early post-operative death (1/13 vs 1/12, χ2 = 0.003), and the duration of hospital stay ［26.0 (18.5~27.5) vs 18.5 (21.5~40.8) d, T=150.500］ of the two groups were no statistically different (P>0.05) . Conclusion Reasonable perioperative management in neonates with TGA/IVS can obtain better short-and long-term efficacy.
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Received: 02 June 2016
Published: 25 January 2018
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