Abstract: 【Abstract】Objectives
To observe the clinical features of neonates with invasive
fungal infections
in the neonatal intensive care unit of the
hospital．Methods
A
retrospective analysis
of the clinical
features，
predisposing factors
and treatment experience in 1 1 cases of invasive
fungal
infections was conducted．Results
All of 1 1 cases，10 cases Was
premature children，9
cases with
gestational age of less
than 34 weeks，7 cases
very
low birth
weight infants，2
cases treated with
peripherally
inserted central
catheter(PICC)and
7 cases
supported by
mechanical ventilation(IMV)．All cases were
receiving intravenous broad—spectrum antibiotics，
parenteral
nutrition and continuous intravenous catheter．From 7 days to 10 days after admission．there were a
number of clinical symptoms such as
poor response，cyanosis，apnea，feeding intolerance，soft limbs，skin
color
pale gray，low
blood
pressure，fever
and SO on．Blood culture ahowed candida
albicans(5 cases)，and nearly
smooth candida yeast(3
cases)．All
cases accepted
anti—fungal，supportive
and
symptomatic
treatment．Ten
patients
were cured and
discharged，and only
one
patient gave up
treatment．Conclusion Neonatal
high
risk
factors for invasive
fungal
infections were
premature birth，long—term application
of broad—spectrum antibiotics，
continuous intravenous catheter and IMV．The clinical
symptoms
were often
atypical，accompanied by
a
decrease in platelet count．The
prognosis would be
favorite if early
diagnosis
and
early
treatment were
given．
2013, Vol. 1 
