脓毒性休克,低血压,平均动脉压," /> 脓毒性休克,低血压,平均动脉压,"/> <span style="font-size:14px;line-height:2;">儿童脓毒性休克低血压参考范围的</span><span style="font-size:14px;line-height:2;">研究现状</span><span style="font-size:14px;line-height:2;"></span>
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发育医学电子杂志  2021, Vol. 9 Issue (5): 386-389    DOI: 10.3969/j.issn.2095-5340.2021.05.011
  生长发育   综述 |
儿童脓毒性休克低血压参考范围的研究现状
林丽曼 柯创宏 黄宇戈
广东医科大学附属医院 儿童医学中心,广东 湛江 524000
Research status of reference range for hypotension in children with septic shock
Lin Liman, Ke Chuanghong, Huang Yuge
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摘要 脓毒症是儿科的常见疾病,死亡率高,是儿童死亡的主要病因之一,全球每年诊断为脓毒症的新生儿约300 万、儿童约120 万[1],大多数由于并发难治性休克和(或)多器官功能障碍综合征在接受治疗后48 ~ 72 h 内死亡[2],根据疾病的严重程度、危险因素等,儿童脓毒症的死亡率为4% ~ 50%[3-5]。儿
童脓毒性休克的诊断与成人的不同之处在于不一定具备低血压,但怀疑有感染的儿童出现低血压一
定是脓毒性休克,且低血压是脓毒性休克代偿期及失代偿期不可逆的重要表现之一[6-9],故血压既是休
克的决定性特征,也是临床工作者治疗的目标,因此尽早识别低血压为挽救生命赢得了救治时间,可显
著降低其病死率及改善预后。在脓毒性休克低血压的最新定义中, 成人的平均动脉压(mean arterial
pressure, MAP)<65 mmHg(1 mmHg=0.133 kPa)为低血压[6-7]。然而,儿童脓毒性休克中低血压的参考范围并没有明确定义,仍存在较大争议,其中包括:MAP、收缩压(systolic blood pressure,SBP)、舒张压(diastolic blood pressure,DBP)以及脉压(pulsepressure, PP)的参考范围。现将近年关于儿童脓毒性休克低血压参考范围研究现状进行综述,希望能给广大儿科医务工作者带来启发和收获。
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关键词:  脓毒性休克')" href="#">脓毒性休克  低血压  平均动脉压')" href="#">平均动脉压    
收稿日期:  2020-09-23                     发布日期:  2021-09-30     
基金资助: 湛江市科技攻关计划项目(2016B01193)
通讯作者:  黄宇戈    E-mail:  Email:gdmcerke@hotmail.com
引用本文:    
林丽曼 柯创宏 黄宇戈. 儿童脓毒性休克低血压参考范围的研究现状[J]. 发育医学电子杂志, 2021, 9(5): 386-389.
Lin Liman, Ke Chuanghong, Huang Yuge. Research status of reference range for hypotension in children with septic shock. Journal of Developmental Medicine(Electronic Version), 2021, 9(5): 386-389.
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