发育医学电子杂志 2021, Vol. 9 Issue (5): 386-389 DOI: 10.3969/j.issn.2095-5340.2021.05.011
生长发育
综述
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儿童脓毒性休克低血压参考范围的 研究现状
林丽曼 柯创宏 黄宇戈
广东医科大学附属医院 儿童医学中心,广东 湛江 524000
Research status of reference range for hypotension in children with septic shock
Lin Liman, Ke Chuanghong, Huang Yuge
摘要 脓毒症是儿科的常见疾病,死亡率高,是儿童 死亡的主要病因之一,全球每年诊断为脓毒症的新 生儿约300 万、儿童约120 万[1] ,大多数由于并发难 治性休克和(或)多器官功能障碍综合征在接受治疗 后48 ~ 72 h 内死亡[2] ,根据疾病的严重程度、危险 因素等,儿童脓毒症的死亡率为4% ~ 50%[3-5] 。儿
童脓毒性休克的诊断与成人的不同之处在于不一 定具备低血压,但怀疑有感染的儿童出现低血压一
定是脓毒性休克,且低血压是脓毒性休克代偿期及 失代偿期不可逆的重要表现之一[6-9] ,故血压既是休
克的决定性特征,也是临床工作者治疗的目标,因此 尽早识别低血压为挽救生命赢得了救治时间,可显
著降低其病死率及改善预后。在脓毒性休克低血 压的最新定义中, 成人的平均动脉压(mean arterial
pressure, MAP)<65 mmHg(1 mmHg=0.133 kPa)为低 血压[6-7] 。然而,儿童脓毒性休克中低血压的参考 范围并没有明确定义,仍存在较大争议,其中包括: MAP、收缩压(systolic blood pressure,SBP)、舒张 压(diastolic blood pressure,DBP)以及脉压(pulse pressure, PP)的参考范围。现将近年关于儿童脓 毒性休克低血压参考范围研究现状进行综述,希 望能给广大儿科医务工作者带来启发和收获。
关键词:
脓毒性休克')" href="#">脓毒性休克
低血压
平均动脉压')" href="#">平均动脉压
收稿日期: 2020-09-23
发布日期: 2021-09-30
基金资助: 湛江市科技攻关计划项目(2016B01193)
通讯作者:
黄宇戈
E-mail: Email:gdmcerke@hotmail.com
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