Journal of Developmental Medicine(Electronic Version)  2022, Vol. 10 Issue (6): 440-446 DOI: 10.3969/j.issn.2095-5340.2022.06.007 |
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| Investigation and analysis of birth defects status in perinatal infants in Guilin, Guangxi Province |
| Fang Yiming , Zeng Jianjuan , Zhao Chaochao, et al
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, Guilin 541199, China; 3.The Guangxi Key Laboratory of Environmental Exposure Mics and Entire Lifecycle Heath, Guangxi, Guilin 541199, China; 4. Guangxi Health Commission Key Laboratory of Entire Lifecycle Health and Care, Guangxi, Guilin 541199, China)
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Abstract 【Abstract】 Objective To analyze the information of perinatal infants with birth defects in Guilin, Guangxi Province from January 2018 to December 2020, and understand the occurrence of birth defects. Method From January 2018 to December 2020, the information of Birth Defects Registration Card of all monitoring hospitals in Guilin, Guangxi Province and medical records of perinatal infants were compiled. Descriptive statistical analysis was performed on the monitoring data and occurrence of birth defects. The number of cases, percentage and constituent ratio were used for statistical analysis. Result From January 2018 to December 2020, a total of 147 817 perinatal infants were enrolled in Guilin, including 2 003 perinatal birth defects. The incidence of birth defects was 135.51/10 000, which was increasing every year. The top three common birth defects were congenital heart disease (CHD), polydactyly and synpolydactyly. Of which CHD was the ?rst, with an incidence of 34.30/10 000, accounting for 25.31% of the total birth defects. Furthermore, the prevalence of birth defects of pregnant women aged 30-34 years was the highest (34.55%，692/2 003), and the prevalence of CHD increased with the increase of maternal age. The constituent ratio of birth defects in rural areas was higher than that in urban areas [(63.70%, 1 276/2 003) vs (36.30%, 727/2 003)]. And the prevalence of birth defects in male perinatal infant was higher than that in female [(59.06%, 1 183/2 003) vs (40.79%, 817/2 003)]. As for diagnosis time, most live birth defects were diagnosed in the time period of "postpartum diagnosis within 7 days" (93.58%, 1 720/1 838), which was mainly diagnosed by clinical methods (68.93%, 1 267/1 838). While most birth defects of non-live births were diagnosed in the period of "prenatal diagnosis" (87.88%, 145/165), which was mainly diagnosed by ultrasound diagnosis methods (60.61%, 100/165). Conclusion From January 2018 to December 2020, the incidence of perinatal birth defects in Guilin, Guangxi Province is generally low, but has a rising trend. CHD is the leading birth defect.
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Received: 04 July 2022
Published: 30 November 2022
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