Journal of Developmental Medicine(Electronic Version)  2024, Vol. 12 Issue (3): 229-234 DOI: 10.3969/j.issn.2095-5340.2024.03.012 |
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| Role of microRNA in pathogenesis and complications of gestational diabetes mellitus |
| Sun Chaoying, Ma Dandan, Zhao E, et al
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(1. Department of Obstetrics, Tianjin People's Hospital,Tianjin 300121, China; 2. Department of Reproductive Medicine and Family Planning, the Second Hospital of Tianjin Medical University, Tianjin 300211, China)
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Abstract 【Abstract】Gestational diabetes mellitus (GDM) is a growing public health problem worldwide, threateningmaternal and newborn health. Through the discovery of its pathophysiological mechanism, it is more targeted in preventing and reducing the occurrence of pregnancy complications. In recent years, microRNA (miRNA),as one of the most common epigenetic mechanisms, have played an important role in the pathophysiology ofpregnancy-related diseases, including GDM. The purpose of this review is to analyze the changes of miRNA in pregnant women with GDM, focusing on the potential of miRNA as a biomarker to predict or diagnose GDM and predict the prognosis of the disease, and to help us explore the pathogenesis and prevention measures of GDM.
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Received: 04 January 2024
Published: 01 June 2024
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