Journal of Developmental Medicine(Electronic Version)  2015, Vol. 3 Issue (1): 35-38 DOI: |
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| Polypronuclear zygotes and clinical pregnancy after in vitro fertilization |
| LI Yan, HUANG Yan-hong, WANG Hai-xu CHEN Bi-liang, ZHOU Dang-xia, HAN Wei
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| 1. Xijing Hospital of Fourth Military Medical University2.Medical School of Xi’an jiaotong University3.Chongqing Health Center for Women and Children |
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Abstract 【Abstract】Objective To study the relationship between the percentage of polypronuclear zygotes and clinical pregnancy following IVF. Method 351 cycles of IVF- ET were analyzed retrospectively and the pregnancy outcomes of different polypronuclear rates were compared． Results The basic situation of the three groups was no statistically significance（P>0.05）. There was no statistically difference in fertilization rate between low frequency polypronuclear group and normal fertilization group（P>0.05）. Fertilization rate in high frequency polypronuclear group was lower than in normal fertilization group, there was statistically significant difference (P<0.05). Good quality embryos rate in low frequency polypronuclear group washigher than in normal fertilization group, there was statistically significant difference (P<0.05). There was no statistically difference in good quality embryos rate between high frequency polypronuclear group and normal fertilization group（P>0.05）. Clinical pregnancy rate in low frequency polypronuclear group was rising, but there was no statistical significance between the two groups（P>0.05）, while, Clinical pregnancy rate in high frequency polypronuclear group was decreasing, but there was still not statistically significant between the two groups（P>0.05）.Conclusions The percentage of polypronuclear zygotes in IVF cycles may serve as a prognostic indicator of the clinical outcome.
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Published: 20 July 2019
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| Fund:国家自然科学基金资助项目（NO.81273018）；第四军医大学西京医院新技术新业务常规项目（编号：XJGX13LC12） |
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