Journal of Developmental Medicine(Electronic Version)  2017, Vol. 5 Issue (2): 98-101 DOI: |
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| Influence of obesity before pregnancy on pregnant outcome of fetal growth restriction |
| XU Gui-jie 1,2, SHANG Li-xin1
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1. Department of Obstetrics & Gynecology, PLA Army General Hospital, Beijing 100700, China;
2. Department of Obstetrics & Gynecology, First Clinical College, The Medical University of Dalian, Liaoning, Dalian 116044, China)
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Abstract Objective To investigate the influence of obesity before pregnancy on pregnant outcome in fetal growth restriction (FGR) patients. Methods From April 1st, 2011 to March 31st, 2016, 213 pregnant women in the department of obstetrics & gynecology, PLA Army General Hospital were enrolled according to the following criteria: regular prenatal examination, single pregnancy, natural pregnancy, without fetal malformations, and being diagnosed as FGR before and after delivery. According to the body mass index (BMI) before pregnancy, 213 cases were divided into three groups, which were normal, overweight and obese groups. The general situation, complications and deaths of perinatal infants were compared among the three groups. Statistical analysis was performed by variance analysis, χ2 test and Fisher's exact test. Results There were no significant differences in the age, gravidity and parity of the three groups (P>0.05). The proportion of the following indicators in the obese group was higher than that in the normal group and overweight group: cesarean section ［86.7% (26/30) vs 47.4% (54/114) and 79.7% (55/69)］, deaths of perinatal infants ［13.3% (4/30) vs 0.0% (0/114) and 1.5% (1/69)］, placental abnormalities ［23.3% (7/30) vs 5.3% (6/114) and 10.1% (7/69)］, gestational diabetes mellitus ［23.3% (7/30) vs 6.1% (7/114) and 15.9% (11/69)］, and preeclampsia ［26.7% (8/30) vs 10.5% (12/114) and 21.7% (15/69)］. In the 8 preeclampsia cases of obese group, 4 cases were severe eclampsia and occurred death of perinatal infants. Conclusions Obese pregnant women with FGR should pay attention to the risk of complications in pregnancy and delivery and intervene reasonably to improve the pregnant outcome.
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Received: 19 November 2016
Published: 17 January 2018
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