Journal of Developmental Medicine(Electronic Version)  2019, Vol. 7 Issue (4): 287-291 DOI: 10.3969/j.issn.2095-5340.2019.04.010 |
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| Analysis of diagnostic value with transvaginal ultrasound on polycystic ovary morphology at different ages |
| SONG Jin, GUAN Huai, CHEN Shi
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| 1. Department of Special Diagnosis, No. 967 Hospital of PLA, Liaoning, Dalian 116021, China; 2. Department of Obstetrics and Gynecology, No. 967 Hospital of PLA, Liaoning, Dalian 116021, China |
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Abstract 【Abstract】 Objective To explore the diagnostic value of ultrasound for polycystic ovary morphology (PCOM) at different ages. Methods From January 2015 to May 2018, 131 women with polycystic ovary syndrome (PCOS) were selected in the Department of Prepotency, No. 967 Hospital of PLA. 135 women with regular menses and no hyperandrogenism were selected as control group simultaneously. Ovarian volume and number of follicle were calculated and transvaginal ultrasound was performed at 3-5 day after menstruation or during the amenorrhoea period. Two groups were further divided into 5 subgroups asfollow: 18-25 (containing 25), 25-30 (containing 30), 30-35 (containing 35), 35-40 (containing 40), 40-45 based on their years old. A receiver operating characteristic (ROC) curve was constructed for working characteristics of the cases in all age groups to determine the optimum diagnostic cutoffs (the maximum value of Yoden index, the best sensitivity and specificity). The ovarian volume or follicle number was used as test variable, and whether to be PCOM as state variable. Results According to the age order of 18-25, 25-30, 30-35, 35-40, 40-45, the ovarian volume of PCOS in all age groups was as follow: (13.5±3.7), (12.0±3.0), (12.1±3.5), (11.3±2.9) and (10.8±3.0) ml respectively, meanwhile the follicle number was as follow: (15.3±3.8), (15.7±4.3), (13.2±4.8), (12.7±4.5) and (11.1±3.7) respectively. The PCOS group was larger than that in the control group in the ovarian volume and follicle number significantly in all age groups (P﹤0.05). Using the ovarian volume as test variable and whether to be PCOM as state variable, the area under the ROC curve was as follow: 0.764, 0.737, 0.809, 0.834 and 0.763, and the value of cutoff was as follow: 13, 10, 9, 9 and 9 ml respectively on the basis of age order. Using the follicle number as test variable and whether to be PCOM as state variable, the area under the curve was as follow: 0.851, 0.846, 0.880, 0.762 and 0.871, and the value of cutoff was as follow: 13, 13, 9, 9 and 9 respectively on the basis of age order. Conclusions The ovarian volume and follicle number threshold for diagnosis as PCOM should be changed with age. Ovarian volume is 13 ml and the number of follicles is 13 at 18-25 years old. Ovarian volume is 10 ml and the number of follicles is 13 at 25-30 years old. Ovarian volume is 9 ml and the number of follicles is 9 at 30-45 years old.
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Received: 24 December 2018
Published: 14 November 2019
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