新生儿坏死性小肠结肠炎,短肠综合征,空肠结肠吻合术," /> 新生儿坏死性小肠结肠炎,短肠综合征,空肠结肠吻合术,"/> <div> <span style="line-height:2;font-size:14px;">新生儿坏死性小肠结肠炎导致短肠综合</span><span style="line-height:2;font-size:14px;">征的营养支持</span> </div>
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发育医学电子杂志  2020, Vol. 8 Issue (3): 272-276    DOI: 10.3969/j.issn.2095-5340.2020.03.015
  围产医学   综述 |新生儿 |
新生儿坏死性小肠结肠炎导致短肠综合征的营养支持
赵晓霞 陈锐 钭金法
国家儿童健康与疾病临床医学研究中心 浙江大学医学院附属儿童医院 新生儿外科,浙江 杭州 310052
Nutritional support of short bowel syndrome in newborn with necrotic enterocolitis
Zhao Xiaoxia, Chen Rui, Dou Jinfa
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摘要 
新 生 儿 坏 死 性 小 肠 结 肠 炎(necrotizingenterocolitis,NEC)是新生儿期一种特有的累及肠道的炎症坏死性疾病。近年来由于早产儿出生增加,新生儿重症监护室水平提高,早产及极低早产儿存活率明显提高,与此相关的 NEC 患儿也有所增多。肠切除及肠造瘘术是治疗 NEC 的主要手术方式,部分 NEC 患儿因病变位置较高,需要进行高位小肠造口,形成暂时性短肠综合征(temporaryshort bowel syndrome,TSBS)。 而 部 分 NEC 患 儿因病变广泛,需要大量肠切除,从而导致短肠综合征(short bowel syndrome,SBS)。儿童 SBS 是指由于小肠大量切除、旷置或先天性短肠等,导致小肠吸收能力受限,无法满足患儿生长发育的需求,需要肠外营养支持 42 d 以上者[1] 。因此 NEC 是 SBS的主要原因之一,NEC 术后 SBS 的临床表现取决于空肠和回肠的剩余长度、肠造口的存在、回盲瓣(ileocecal valve,ICV)的存在、结肠的剩余长度等。本综述结合文献资料,讨论分析 NEC 导致的不同类型 SBS 的肠适应及营养支持等特点。
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关键词:  新生儿坏死性小肠结肠炎')" href="#">新生儿坏死性小肠结肠炎  短肠综合征')" href="#">短肠综合  空肠结肠吻合术    
收稿日期:  2020-04-16                出版日期:  2020-07-30      发布日期:  2020-07-28      期的出版日期:  2020-07-30
基金资助: 
浙江省自然科学基金(LQ19H030012)
通讯作者:  钭金法https://person.zju.edu.cn/6198008    E-mail:  toujinfa@zju.edu.cn
引用本文:    
赵晓霞 陈锐 钭金法.
新生儿坏死性小肠结肠炎导致短肠综合征的营养支持
[J]. 发育医学电子杂志, 2020, 8(3): 272-276.
Zhao Xiaoxia, Chen Rui, Dou Jinfa.
Nutritional support of short bowel syndrome in newborn with necrotic enterocolitis
. Journal of Developmental Medicine(Electronic Version), 2020, 8(3): 272-276.
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http://www.fyyxzz.com/CN/10.3969/j.issn.2095-5340.2020.03.015  或          http://www.fyyxzz.com/CN/Y2020/V8/I3/272
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