发育医学电子杂志 2020, Vol. 8 Issue (3): 272-276 DOI: 10.3969/j.issn.2095-5340.2020.03.015
围产医学
综述
|新生儿
|
新生儿坏死性小肠结肠炎导致短肠综合 征的营养支持
赵晓霞 陈锐 钭金法
国家儿童健康与疾病临床医学研究中心 浙江大学医学院 附属儿童医院 新生儿外科,浙江 杭州 310052
Nutritional support of short bowel syndrome in newborn with necrotic enterocolitis
Zhao Xiaoxia, Chen Rui, Dou Jinfa
摘要
新 生 儿 坏 死 性 小 肠 结 肠 炎(necrotizing enterocolitis,NEC)是新生儿期一种特有的累及肠 道的炎症坏死性疾病。近年来由于早产儿出生增 加,新生儿重症监护室水平提高,早产及极低早产 儿存活率明显提高,与此相关的 NEC 患儿也有所 增多。肠切除及肠造瘘术是治疗 NEC 的主要手术 方式,部分 NEC 患儿因病变位置较高,需要进行 高位小肠造口,形成暂时性短肠综合征(temporary short bowel syndrome,TSBS)。 而 部 分 NEC 患 儿 因病变广泛,需要大量肠切除,从而导致短肠综合 征(short bowel syndrome,SBS)。儿童 SBS 是指由 于小肠大量切除、旷置或先天性短肠等,导致小肠 吸收能力受限,无法满足患儿生长发育的需求,需 要肠外营养支持 42 d 以上者[1] 。因此 NEC 是 SBS 的主要原因之一,NEC 术后 SBS 的临床表现取决 于空肠和回肠的剩余长度、肠造口的存在、回盲瓣 (ileocecal valve,ICV)的存在、结肠的剩余长度等。 本综述结合文献资料,讨论分析 NEC 导致的不同 类型 SBS 的肠适应及营养支持等特点。
关键词:
新生儿坏死性小肠结肠炎')" href="#">新生儿坏死性小肠结肠炎
短肠综合征')" href="#"> 短肠综合 征
空肠结肠吻合术
收稿日期: 2020-04-16
出版日期: 2020-07-30
发布日期: 2020-07-28
期的出版日期: 2020-07-30
基金资助:
浙江省自然科学基金(LQ19H030012)
通讯作者:
钭金法https://person.zju.edu.cn/6198008
E-mail: toujinfa@zju.edu.cn
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