发育医学电子杂志 2021, Vol. 9 Issue (1): 1-7 DOI: 10.3969/j.issn.2095-5340.2021.01.001 |
发育基础
专题笔谈
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前列腺癌分子机制及其动物模型 |
张富娟 赵旭东 孙彬
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四川大学华西医院 肿瘤动物模型创制及应用研究室,四川 成都 610041
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Molecular mechanism and animal models of prostate cancer |
Zhang Fujuan, Zhao Xudong, Sun Bin |
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摘要 在生命体发育和衰老的过程中,细胞在特定的信号调控下有序地进行生长、分化和(或)凋亡。然
而,细胞分裂过程中自然积累的突变和许多外界因素,如射线、化学致癌物、病毒等诱导的突变可导致癌基因激活、抑癌基因失活,从而破坏了正常的细胞调控网络,引起细胞异常增殖与持续分裂 , 导致
肿瘤产生。
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关键词:
前列腺癌')" href="#">前列腺癌
分子机制
基因工程鼠模型
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收稿日期: 2020-11-11
发布日期: 2021-01-28
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基金资助:
国家自然科学基金 (U1702289)
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通讯作者:
孙彬
E-mail: Email:sunbin@wchscu.cn
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