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发育医学电子杂志  2024, Vol. 12 Issue (1): 47-52    DOI: 10.3969/j.issn.2095-5340.2024.01.009
  生长发育   论著 |
中文版电休克治疗认知评估量表在成年早期抑郁症患者中的心理测量特征研究
于红晔 刘君 沙莎
首都医科大学附属北京安定医院 抑郁症治疗中心临床5 病区,北京 100088)
Psychometric characteristics of the Chinese version of the electroconvulsive therapy cognitive assessment in early adult patients with depression
Yu Hongye, Liu Jun, Sha Sha 
Ward 5, Depression Treatment Center, Beijing Anding Hospital, CapitalMedical University, Beijing 100088, China)
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摘要 【摘要】 目的  探讨中文版电休克治疗认知评估(electroconvulsive therapy cognitive assessment,ECCA)量表在成年早期抑郁症患者中的心理测量特征。 方法 本研究于2021 年1 月至2022 年12 月在
首都医科大学附属北京安定医院进行。最终共纳入成年早期抑郁症患者40 例,健康对照组30 例。对
接受电休克治疗(electroconvulsive therapy,ECT)的成年早期抑郁症患者在3 个时间点进行ECCA 和
蒙特利尔认知评估(Montreal cognitive assessment,MoCA),即治疗前(基线)、第5 次治疗后和治疗结束后5~10 d。健康受试者进行1 次ECCA 评估。统计学分析采用χ2 检验、重复测量方差分析、t 检验、
Pearson 相关性分析。 结果  成年早期抑郁症组与对照组的年龄、性别、受教育年限比较,差异均
无统计学意义(P 值均>0.05)。但成年早期抑郁症组的ECCA 基线评分低于对照组[(27.75±1.77)与
(29.10±0.80)分,t=-3.687,P<0.001];MoCA 基线评分低于对照组[(27.39±0.23)与(29.60±0.30)分,t=-11.640,P<0.001]。ECCA 内部一致性分析中的Cronbach'α 系数为0.811(P<0.001)。ECCA 评分ECT前[(27.75±1.77)分]>ECT 中[(25.17±1.73)分]>ECT 后[(21.90±3.67)分](F=13.242,P 值均<0.001),而MoCA 评分在这3 个时间点比较,差异无统计学意义(F=1.871,P=0.171)。在排除性别、年龄、教育水平的影响因素后,ECCA 总分与基线时成年早期抑郁症患者的MoCA 评分(r=0.450,P<0.01)和汉密尔顿抑郁量表(Hamilton depression scale-17 item,HDRS-17)评分(r=-0.621,P<0.01)有关。 结论 中文版ECCA 具有较好的心理测量特性,可作为成年早期抑郁症患者中评估ECT 相关认知损害的临床应用工具。
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关键词:  电休克治疗  成年早期  抑郁症  认知损害    
Abstract: 【Abstract】 Objective To explore the psychometric characteristics of the Chinese version of the
electroconvulsive therapy cognitive assessment (ECCA) in early adult patients with depression.
Method The study was conducted at Beijing Anding Hospital, Capital Medical University from January
2021 to December 2022. Finally, a total of 40 early adults with depression and 30 healthy controls were
included. ECCA and the Montreal cognitive assessment (MoCA) were performed at three time points in early adults with depression who were treated with electroconvulsive therapy (ECT). That is, before treatment(baseline), after the fifth treatment, and 7-10 days after the end of treatment. Healthy subjects underwent anECCA assessment. Statistical analysis performed by χ2 test, repeated measurements of ANOVA, t-test, Pearson correlation analysis.  Result There were no significant differences in age, gender and years of educationbetween the depression group and the control group (all P>0.05). However, the baseline ECCA score in theearly adult depression group was lower than that in the control group [(27.75±1.77) vs (29.10±0.80) points,t=-3.687, P<0.001]. The baseline MoCA score was lower than that of the control group [(27.39±0.23) vs(29.60±0.30) points, t=-11.640, P<0.001]. Cronbach'α in ECCA internal consistency analysis was 0.811(P<0.001). ECCA scores before ECT [(27.75±1.77) points] > during ECT [(25.17±1.73) points] > afterECT [(21.90±3.67) points] (F=13.242,all P<0.001), while MoCA scores at these three time points showedno significant difference (F=1.871, P=0.171). After controlling for gender, age, and education level, thetotal ECCA score was highly correlated with MoCA (r=0.450, P<0.01) and Hamilton depression scale-17tem (HDRS-17) (r=-0.621, P<0.01) at baseline in early adult patients with depression. Conclusion TheChinese version of ECCA has good psychometric characteristics and can be used as a clinical tool to assessECT related cognitive impairment in early adult patients with depression.
Key words:  Electroconvulsive therapy    Early adulthood    Depression    Cognitive impairment
收稿日期:  2023-04-18                     发布日期:  2024-01-31     
通讯作者:  沙莎    E-mail:  shasha@mail.ccmu.edu.cn
引用本文:    
于红晔 刘君 沙莎. 中文版电休克治疗认知评估量表在成年早期抑郁症患者中的心理测量特征研究[J]. 发育医学电子杂志, 2024, 12(1): 47-52.
Yu Hongye, Liu Jun, Sha Sha . Psychometric characteristics of the Chinese version of the electroconvulsive therapy cognitive assessment in early adult patients with depression. Journal of Developmental Medicine(Electronic Version), 2024, 12(1): 47-52.
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http://www.fyyxzz.com/CN/10.3969/j.issn.2095-5340.2024.01.009  或          http://www.fyyxzz.com/CN/Y2024/V12/I1/47
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[2] 黄颀 曾祥丽. 三亚市孕妇缺铁性贫血与抑郁症的相关性研究[J]. 发育医学电子杂志, 2023, 11(1): 38-43.
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