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发育医学电子杂志  2024, Vol. 12 Issue (6): 451-456    DOI: 10.3969/j.issn.2095-5340.2024.06.007
  围产医学   论著 |新生儿 |
新生儿泪囊炎发病危险因素分析
周文轲 何俐莹 陶雪莹 岑超 黎琦
重庆市妇幼保健院 重庆医科大学附属妇女儿童医院 眼耳鼻喉科,重庆 400000
Analysis of risk factors of neonatal dacryocystitis
Zhou Wenke, He Liying, Tao Xueying, et al
(Department of Ophthalmology,Otorhinolaryngology, Chongqing Health Center for Women and Children, Women and Children’s Hospital of Chongqing Medical University, Chongqing 400000, China)
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摘要 【摘要】 目的  探讨新生儿泪囊炎发病的影响因素,研究泪道冲洗的最优时机,以便为新生儿泪囊炎的预
防和治疗提供可靠的临床依据。 方法 采用回顾性病例对照研究方法,收集2019 年3 月至2022 年8 月
在重庆市妇幼保健院诊治的新生儿泪囊炎患儿553 例以及正常对照组553 例,对照组为非调查因素相
同的非新生儿泪囊炎。在病历系统中提取孕母病史、分娩方式以及新生儿胎龄、出生体质量等相关信息,
对比不同月龄新生儿首次行泪道冲洗后泪囊炎的治愈率。统计学方法采用单因素和多因素Logistic 回
归分析以及χ2 检验。 结果  多因素Logistic 回归分析结果表明,剖宫产、男婴、母亲妊娠期合并全
身疾病是新生儿泪囊炎发病的危险因素(P 值均<0.05)。剖宫产新生儿罹患泪囊炎的概率是顺产的
1.279 倍,妊娠期合并全身疾病孕妇娩出新生儿罹患泪囊炎的概率是妊娠期健康孕妇的1.399 倍。而出
生胎龄、出生体质量、孕妇民族等与新生儿泪囊炎均无统计学差异(P 值均>0.05)。首次行泪道冲洗月
龄不同,新生儿泪囊炎的治愈率差异有统计学意义(P=0.038),且行泪道冲洗治愈率最高的泪囊炎患儿首
次冲洗月龄为2~3 月龄(治愈率为28.25%)。 结论 剖宫产、男婴、母亲妊娠期合并全身疾病可能会导
致新生儿泪囊炎的发生,加强孕期保健宣教,在各方面条件合适的情况下鼓励孕妇自然分娩,可有效减
少新生儿泪囊炎的发生。对于新生儿泪囊炎患儿,建议首次冲洗月龄为2~3 月龄。
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关键词:  新生儿泪囊炎  发病危险因素  泪道冲洗  回归分析    
Abstract: 【Abstract】 Objective To investigate the influencing factors of neonatal dacryocystitis and explore the
best time for irrigation of lacrimal passage, so as to provide a reliable clinical basis for the prevention and
treatment of neonatal dacryocystitis. Method A retrospective case-control study was used to collect
553 cases of neonatal dacryocystitis treated in Chongqing Health Center for Women and Children from
March 2019 to August 2022 and 553 cases of normal control group. The control group was non-neonatal
dacryocystitis with the same non-investigation factors. Relevant information such as maternal medical history,delivery mode, gestational age and fetal weight of infants were extracted from the medical record system, the cure rate of neonatal dacryocystitis after first irrigation of lacrimal passage at different months was compared. The statistical methods performed by univariate analysis and multivariate Logistic regression analysis, χ2 test. Result The results of multivariate Logistic regression analysis showed that cesarean section, male, maternalpregnancy combined with systemic disease were the risk factors for neonatal dacryocystitis (all P <0.05), theprobability of neonatal dacryocystitis during cesarean section was 1.279 times that of vaginal delivery, and the probability of dacryocystitis in newborns of pregnant women with systemic diseases during pregnancywas 1.399 times that of healthy pregnant women during pregnancy. Gestational age, birth weight of infantsand maternal ethnicity were not significantly different from neonatal dacryocystitis (all P>0.05). The cure rate of neonatal dacryocystitis was statistically significant with different months of first irrigation of lacrimal passage (P=0.038), and the highest cure rate of the first irrigation of lacrimal passage was 2 to 3 months (the cure rate was 28.25%). Conclusion Cesarean section, male and maternal pregnancy combined with systemic diseases may lead to neonatal dacryocystitis. Strengthening the health education during pregnancy and encourage pregnant women to give birth naturally under appropriate conditions, which can effectively reduce the occurrence of neonatal dacryocystitis. For children with neonatal dacryocystitis, it is recommended that the first irrigation of lacrimal passage was 2 to 3 months.
Key words:  Neonatal dacryocystitis    Pathogenic risk factors    Lacrimal duct irrigation    Regression analysis
收稿日期:  2023-09-10                     发布日期:  2024-11-27     
基金资助: 重庆市社会事业与民生保障科技创新专项重点研发资助项目(cstc2017shms-zdyfX0049)
通讯作者:  何俐莹    E-mail:  489574008@qq.com
引用本文:    
周文轲 何俐莹 陶雪莹 岑超 黎琦. 新生儿泪囊炎发病危险因素分析[J]. 发育医学电子杂志, 2024, 12(6): 451-456.
Zhou Wenke, He Liying, Tao Xueying, et al. Analysis of risk factors of neonatal dacryocystitis. Journal of Developmental Medicine(Electronic Version), 2024, 12(6): 451-456.
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