Risk factors analysis of 38 cases of perinatal digestive system abnormalities#br#
GUAN Huai, GUO Yi, GUO Yan-jie, et al
GUAN Huai 1, GUO Yi 2, GUO Yan-jie 3,SHANG Li-xin 4, LIU Dun 1, WEN Zhu 1(1.Department of Obstetrics and Gynecology,No. 210 Hospital of PLA,Dalian,116021, China; 2.Department of Obstetrics, Dalian Obstetrics and Gynecology Hospital, Dalian 116033, China ; 3.Department of Microecology,Dalian Medical University,Dalian,116044, China;4.Department of Obstetrics and Gynecology, General Hospital of Beijing Military Command, 100700 Beijing, China)
Abstract: Objective To investigate the influencing factors relating to development of digestive system malformation so as to provide evidences for understanding and controlling this birth defect. Method A total of 38 stillbirth diagnosed by prenatal ultrasound examination and autopsy after induced labor were selected as study group. A total of 190 term live births were selected as control group. The relevant factors including the general characteristics and parental information were studied by statistical analysis. Results Maternal age of study group was significantly higher than that of the control group (P<0.05). The percentages of pregnancy and parity times≥2 were both significantly higher in study group than those of the control group (P<0.05). The percentages of paternal age≥40 years and paternal exposure to occupational harmful factors were both significantly higher in study group than those of the control group (P<0.05). There were significant differences in the level of education between the two groups (P<0.05). Conclusions Some factors such as parental age, education, maternal parity of child, and paternal exposure to occupational harmful factors may be associsted with the development of digestive system malformation.
2016, Vol. 4 
