Abstract: Objective To analyze the symptoms of perimenopausal and postmenopausal women, and to explore the related factors of perimenopausal symptoms. Methods From March 1st to November 30th, 2012, among the patients who visited reproductive and endocrine clinic of department of gynaecology & obstetrics in the Second Xiangya Hospital of Central South University, totally 120 cases of perimenopausal or postmenopausal women were included. Uniform questionnaire was used. The patients were divided into two groups according to the evaluation of perimenopausal symptoms by improved Kupermann scoring method, Kupermann score≥17 points (group A, 53 cases) and Kupermann score<17 points (group B, 67 cases). The perimenopausal symptoms were analyzed. The general information, incidence of symptoms, menstrual history and treatment were compared between group A and group B. Statistical analysis was used by t test, χ2 test and Fisher's exact test. Results 119 patients (99.2%, 119/120) showed symptoms of different degrees. The five most common symptoms successively were excitement (71.7%), fatigue (68.3%), insomnia (65.8%), sweat and hot flash (64.2%) and ache of bone, joint and muscle (62.5%). There was no significant difference on the age, place of residence, marital status , level of education and high blood pressure, diabetes, uterine fibroids and ovarian surgery history between the two groups (all P﹥0.05). The incidence of various symptoms in group A were higher than that in group B (all P﹤0.05). Moreover, the menarche age, the proportion of delayed menarche age and the proportion of irregular menstruation in reproductive stage in group A were higher than that in group B (all P﹤0.05). Menarche age and Kupermann scores were positive correlated (r=0.224, P = 0.007). Among the 120 patients, 39 cases (32.5%) were receiving hormone replacement therapy (HRT), 39.6% among group A and 26.9% among group B (P﹥0.05). 78 cases (65.0%) knowed of HRT, 56.6% among group A and 71.6% among group B (P﹥0.05). Conclusions The women with delayed menarche or irregular menstruation period have severe symptoms that should be paid more attention and taken active treatment. Some of the women in Changsha know of HRT, but relevant health education should be carried out.
符书馨 李娜 罗辰. 围绝经期症状及相关因素分析[J]. 发育医学电子杂志, 2017, 5(2): 78-82.
FU Shu-xin, LI Na, LUO Chen. Analysis for symptoms of perimenopause and related factors. Journal of Developmental Medicine(Electronic Version), 2017, 5(2): 78-82.
2017, Vol. 5 
