发育医学电子杂志  2021, Vol. 9 Issue (1): 1-7 DOI: 10.3969/j.issn.2095-5340.2021.01.001 |
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发育基础
专题笔谈
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| 前列腺癌分子机制及其动物模型 |
张富娟 赵旭东 孙彬
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四川大学华西医院 肿瘤动物模型创制及应用研究室，四川 成都 610041
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| Molecular mechanism and animal models of prostate cancer |
| Zhang Fujuan, Zhao Xudong, Sun Bin |
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摘要 在生命体发育和衰老的过程中，细胞在特定的信号调控下有序地进行生长、分化和（或）凋亡。然
而，细胞分裂过程中自然积累的突变和许多外界因素，如射线、化学致癌物、病毒等诱导的突变可导致癌基因激活、抑癌基因失活，从而破坏了正常的细胞调控网络，引起细胞异常增殖与持续分裂 , 导致
肿瘤产生。
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| 关键词:
前列腺癌')" href="#">前列腺癌
分子机制
基因工程鼠模型
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收稿日期: 2020-11-11
发布日期: 2021-01-28
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| 基金资助:
国家自然科学基金 （U1702289）
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通讯作者:
孙彬
E-mail: Email：sunbin@wchscu.cn
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