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发育医学电子杂志  2023, Vol. 11 Issue (3): 194-198,204    DOI: 10.3969/j.issn.2095-5340.2023.03.006
  围产医学   论著 |新生儿 |
新生儿溶血病患儿出院后经皮黄疸监测的互联网远程随访研究
刘瑛 杨立
北京市通州区妇幼保健院 新生儿科,北京 101100
Internet remote follow-up study on percutaneous jaundice monitoring of neonatal hemolyticdisease after discharge
Liu Ying, Yang Li
(Department of Neonatology, Tongzhou District Maternal and Child Health Hospital,Beijing 101100, China)
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摘要 【摘要】 目的  探讨新生儿溶血病患儿出院后经皮黄疸监测的互联网远程随访的可行性。 方法 选取2018 年1 月至2020 年10 月在北京市通州区妇幼保健院住院治疗的106 例ABO 血型不合溶血性黄疸患儿进行研究。采用随机数字表法将患儿分为对照组和观察组,每组53 例。对照组患儿给予常规出院随访行黄疸监测,观察组在常规随访基础上加以互联网远程经皮黄疸监测。比较两组患儿胆红素脑病发生率、再入院率、母亲负性情绪[焦虑自评量表(self-rating anxiety scale,SAS)及抑郁自评量表(self-rating depression scale,SDS)]及患儿发育情况(体长、头围、体质量、总发育商)。统计学方法采用t 检验、χ2 检验或Fisher 确切概率法。 结果  观察组患儿的胆红素脑病的发生率[0(0/53)与7.6%(4/53),P=0.041],再入院率[3.8%(2/53)与15.1%(8/53),χ2=3.975,P=0.046]均低于对照组。出院后1 周,观察组患儿的SAS 得分[(14.9±3.6)与(25.0±6.3)分,t=10.192,P<0.001],SDS 得分[(12.9±3.6)与(20.1±5.8)分,t=7.687,P<0.001]均低于对照组。出院时,两组患儿体长、头围、体质量及总发育商差异均无统计学意义(P 值均>0.05)。出院后6 个月,观察组与对照组患儿的体长[(64.7±5.2)与(62.1±4.8)cm,t=-2.644,P=0.009]、头围[(47.6±4.0)与(44.1±3.3)cm,t=-5.008,P<0.001]、体质量[(7.1±0.8)与(6.8±0.6) kg,t=-2.170,P=0.032]及总发育商[(73.1±12.5)与(68.0±11.8)分,t=-2.168,P=0.032]比较,观察组均高于对照组。 结论 ABO 血型不合溶血性黄疸患儿出院后,在常规随访的基础上加以互联网远程随访经皮黄疸监测,有助于降低患儿胆红素脑病发生率、再入院率,缓解母亲不良情绪并改善患儿的生长发育状况。
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关键词:  互联网  经皮黄疸监测  ABO 血型不合溶血性黄疸  生长发育  焦虑自评量表  抑郁自评量表    
Abstract: 【Abstract】 Objective To investigate the feasibility of Internet remote follow-up for percutaneous
jaundice monitoring of neonatal hemolytic disease after discharge. Method From January 2018 to
October 2020, 106 neonates with ABO blood group incompatibility hemolytic jaundice in Tongzhou District
Maternal and Child Health Hospital were selected for the study. The neonates were divided into control groupand observation group with a random number table method, with 53 cases in each group. The neonates in thecontrol group received routine discharge follow-up for jaundice monitoring. On this basis, the observationgroup was followed up by the Internet remote percutaneous jaundice monitoring. The incidence of bilirubinencephalopathy, readmission rate, mother's negative emotions [self-rating anxiety scale (SAS) and selfratingepression scale (SDS)] and children's development (body length, head circumference, body mass,total development quotient) were compared between the two groups. The statistical methods performed byt test, χ2 test or Fisher exact probability method.  Result The incidence of bilirubin encephalopathy [0(0/53) vs 7.6% (4/53), P=0.041], the readmission rates [3.8% (2/53) vs 15.1% (8/53), χ2=3.975, P=0.046]were lower in the observation group than those in the control group. One week after discharge, the SASscores [(14.9±3.6) vs (25.0±6.3) points, t=10.192, P<0.001], the SDS scores [(12.9±3.6) vs (20.1±5.8)points, t=7.687, P<0.001], were lower in the observation group than those in the control group. There wasno significant difference in body length, head circumference, body mass and total developmental quotientbetween the two groups at discharge (all P>0.05). Six months after discharge, the body length [(64.7±5.2) vs(62.1±4.8) cm, t=-2.644, P=0.009], head circumference [(47.6±4.0) vs (44.1±3.3) cm, t=-5.008, P<0.001],body weight [(7.1±0.8) vs (6.8±0.6) kg, t=-2.170, P=0.032] and total development quotient [(73.1±12.5)vs (68.0±11.8) points, t=-2.168, P=0.032] in the observation group were higher than those in the controlgroup. Conclusion After discharge of the neonates with ABO blood group incompatibility hemolyticjaundice, remote Internet follow-up percutaneous jaundice monitoring based on the routine follow-up planis helpful to reduce the incidence of bilirubin encephalopathy and readmission rate, relieve the mother's bad mood and improve the growth and development of the neonates.
Key words:  Internet    Percutaneous jaundice monitoring    ABO blood group incompatibility hemolyticjaundice;    Growth and development    Self-rating anxiety scale    Self-rating depression scale
收稿日期:  2022-07-28                出版日期:  2023-05-31      发布日期:  2023-05-31      期的出版日期:  2023-05-31
基金资助: 北京市卫生健康科技成果和适宜技术推广项目(BHTPP202019)
 
通讯作者:  刘瑛    E-mail:  593272934@qq.com
引用本文:    
刘瑛 杨立. 新生儿溶血病患儿出院后经皮黄疸监测的互联网远程随访研究[J]. 发育医学电子杂志, 2023, 11(3): 194-198,204.
Liu Ying, Yang Li. Internet remote follow-up study on percutaneous jaundice monitoring of neonatal hemolyticdisease after discharge. Journal of Developmental Medicine(Electronic Version), 2023, 11(3): 194-198,204.
链接本文:  
http://www.fyyxzz.com/CN/10.3969/j.issn.2095-5340.2023.03.006  或          http://www.fyyxzz.com/CN/Y2023/V11/I3/194
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