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发育医学电子杂志  2015, Vol. 3 Issue (1): 14-17    
  围产医学   专题笔谈 |产科 |
囊胚培养的利与弊
孙正怡 甄璟然 王雪 郁琦
中国医学科学院北京协和医院
The advantages and disadvantages of blastocyst culture
SUN Zheng-yi,ZHEN Jing-ran,WANG Xue,et al
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摘要 自1978年第1例体外受精-胚胎移植治疗获得成功以来,人胚胎进行体外培养的流程和时间就一直是全世界胚胎学家着重考虑的技术关键点,将人的胚胎在体外培养5~6天,其中发育潜能更好的胚胎有可能会发育成囊胚,形成囊胚的胚胎非整倍体率有明显下降,因此进行移植后能够改善着床率,从而改善临床结局,减少移植胚胎的数目,进而减少多胎的发生。囊胚的体外培养时间
延长,而且囊胚细胞数比较多,因此大大利于植入前遗传学诊断的进行。近年来行囊胚活检后进行遗传学诊断的研究发现,这种方式筛选后的胚胎,着床率可以高达70%左右。本文对囊胚培养技术在辅助生殖治疗中的应用,以及可能带来的风险做一介绍。
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关键词:  体外受精   胚胎移植  囊胚    
收稿日期:  2014-03-15                出版日期:  2015-01-30      发布日期:  2019-07-19      期的出版日期:  2015-01-30
引用本文:    
孙正怡 甄璟然 王雪 郁琦. 囊胚培养的利与弊[J]. 发育医学电子杂志, 2015, 3(1): 14-17.
SUN Zheng-yi, ZHEN Jing-ran, WANG Xue, et al. The advantages and disadvantages of blastocyst culture. Journal of Developmental Medicine(Electronic Version), 2015, 3(1): 14-17.
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http://www.fyyxzz.com/CN/  或          http://www.fyyxzz.com/CN/Y2015/V3/I1/14
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