发育医学电子杂志 2015, Vol. 3 Issue (1): 14-17
围产医学
专题笔谈
|产科
|
囊胚培养的利与弊
孙正怡 甄璟然 王雪 郁琦
中国医学科学院北京协和医院
The advantages and disadvantages of blastocyst culture
SUN Zheng-yi,ZHEN Jing-ran,WANG Xue,et al
摘要 自1978年第1例体外受精-胚胎移植治疗获得成 功以来,人胚胎进行体外培养的流程和时间就一 直是全世界胚胎学家着重考虑的技术关键点,将 人的胚胎在体外培养5~6天,其中发育潜能更好 的胚胎有可能会发育成囊胚,形成囊胚的胚胎非 整倍体率有明显下降,因此进行移植后能够改善 着床率,从而改善临床结局,减少移植胚胎的数 目,进而减少多胎的发生。囊胚的体外培养时间
延长,而且囊胚细胞数比较多,因此大大利于植 入前遗传学诊断的进行。近年来行囊胚活检后进 行遗传学诊断的研究发现,这种方式筛选后的胚 胎,着床率可以高达70%左右。本文对囊胚培养技 术在辅助生殖治疗中的应用,以及可能带来的风 险做一介绍。
关键词:
体外受精
胚胎移植
囊胚
收稿日期: 2014-03-15
出版日期: 2015-01-30
发布日期: 2019-07-19
期的出版日期: 2015-01-30
[1]
GAO Xiao-hui, MAO Jian. Clinical features of non-oliguric hyperkalemia in extremely low birth weight infants [J]. Journal of Developmental Medicine(Electronic Version), 0, (): 152
.
[2]
Society of Neonatologist, Chinese Medical Doctor Association. Consensus recommendations on the prevention and early management of respiratory distress syndrome in preterm infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 129
-131
.
[3]
Professional Committee of Respiratory, Society of Neonatologist, Chinese Medical Doctor Association. Clinical application recommendations for heated humidified high flow nasal cannula [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 132
-135
.
[4]
YAN Jun, ZHU Xing-wang, SHI Yuan. Application progress of noninvasive ventilate technique for premature infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 136
-140
.
[5]
GU Min-fang, YANG Chuan-zhong. Progress of intrapartum resuscitation for premature infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 141
-145
.
[6]
LIU Shu-hua, SHEN Yue-bo, LIU Cui-qing, MA Li. The efficacy of pulmonary surfactant for pulmonary function in premature tension pneumothorax [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 146
-151
.
[7]
GAO Xiao-hui, MAO Jian. Clinical features of non-oliguric hyperkalemia in extremely low birth weight infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 152
-158
.
[8]
XIA Yao-fang, YANG Juan , TIAN Bao-li, et al. Value of amplitude-integrated electroencephalography in monitoring acute period of neonatal bilirubin encephalopathy and prognostic assessment [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 159
-163
.
[9]
WANG Li-rong, SUN Xiao-yan, ZHU Ruo-xin, et al. Epidemiological investigation and analysis of women aged 40-55 years old with osteoporosis in Gansu province [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 164
-167
.
[10]
CHEN Ru-yue, SHEN Yun-yan, CHEN Qing , et al. Five cases about Henoch-Schönlein purpura complicated with central nervous system injury in children and literatures review [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 168
-171
.
Viewed
Full text
Abstract
Cited
Shared
Discussed