Abstract: Objective To analyze the clinical characteristics and outcomes of central nervous system damage in children with Radix Sophorae Subprostratae poisoning, and to provide reference for clinical diagnosis and treatment. Methods From June 2012 to May 2016, 10 children with Radix Sophorae Subprostratae poisoning were admitted to the pediatric department of Xijing Hospital of the Fourth Military Medical University. Clinical manifestations, head MRI results, treatment and outcomes were analyzed retrospectively. Results The first symptoms of three cases was gastrointestinal symptoms, and that of seven cases were dizziness or headache. Ten cases all showed neurological manifestations, including lower extremity ataxia, limb weakness, salivation, aphasia, convulsions, blurred vision and disturbance of consciousness. Nine cases underwent head MRI examination. The results of three cases were normal, and six cases were found cerebellar lesions. After gastric lavage, rehydration, diuretic, improving metabolism, dehydration, neurotrophic and other treatments, nine cases were clinically cured and discharged, but one case with respiratory failure was given up and died. Followed up until May 2016, eight cases showed no neurological sequelaes, and one case was lost to followed-up. Conclusions Radix Sophorae Subprostratae poisoning was harmful to children. Central nervous system damage was the main manifestation. Prevention must be paid attention. Diagnosis and treatment must be performed if poisoning.
牛焕红 范芳. 山豆根中毒致儿童中枢神经系统损害10例[J]. 发育医学电子杂志, 2017, 5(1): 25-27.
NIU Huan-hong, FAN Fang. The report of 10 cases about central nervous system damage caused by Radix Sophorae Subprostratae poisoning in children. Journal of Developmental Medicine(Electronic Version), 2017, 5(1): 25-27.
2017, Vol. 5 
