发育医学电子杂志 2022, Vol. 10 Issue (5): 397-400 DOI: 10.3969/j.issn.2095-5340.2022.05.013
生长发育
综述
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父亲相关因素对儿童过敏性疾病影响的 研究进展
陈俊蓉 董运鹏 李健
1. 湖南师范大学医学院 护理系,湖南 长沙 410006;2. 宜昌市中心人民医院 耳鼻喉头颈外科,湖北 宜昌 443000
Research progress on the influence of paternal on allergic diseases in children
Chen Junrong, Dong Yunpeng, Li Jian
摘要 儿童常见的过敏性疾病有哮喘、过敏性鼻炎、 湿疹、食物过敏。研究发现,不同地区与种族之间 过敏性疾病的种类和发生率有着很大差异[1-3] ,提 示遗传因素、环境暴露、生活习惯和地理位置起着 重要作用。“ 健康与疾病发育起源”(developmental origins of health and disease,DOHaD)学说提示早期 胚胎发育时的不良暴露会增加子代各种疾病的风 险。近年来对儿童过敏性疾病生命发育早期的研 究集中在遗传和环境影响因素方面,以往的危险因 素研究多针对母亲因素[4] ,包括母亲孕前、孕期因 素以及胎儿出生后早期生活环境的不良因素探讨, 然而近年来研究表明父亲亦在子代过敏性疾病的 发生中有重要影响。为了更加全面认识儿童过敏 性疾病的危险因素,本文旨在讨论儿童过敏性疾病 的父亲相关影响因素及机制。
关键词:
儿童
父亲
过敏性疾病
影响因素
收稿日期: 2022-01-04
发布日期: 2022-09-30
基金资助: 国家自然科学基金面上项目(81873861)
通讯作者:
李健
E-mail: lijianyxy@hunnu.edu.cn
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