Clinical analysis of solid pseudopapillary tumor of pancreas in children
Guo Rundong, Yang Shulong, Tai Sheng, et al
1.Department of Pediatric Surgery, theSecond Affiliated Hospital, Harbin Medical University, Heilongjiang, Harbin 150006, China; 2.Departmentof General Surgery, the Second Affiliated Hospital, Harbin Medical University, Heilongjiang, Harbin 150006,China
Abstract: 【Abstract】 Objective To explore the clinical characteristics, diagnosis and treatment of solid pseudopapillary tumor of pancreas (SPTP) in children. Methods The clinical data of 23 patients with SPTP in the Second Affiliated Hospital, Harbin Medical University from September 2010 to March 2021 were analyzed retrospectively. The clinical manifestations, imaging features, tumor location, pathology, surgical treatment and prognosis to summarize the treatment experience were analyzed. Results The average age of 23 patients was (13±3) years, including 2 males and 21 females. The tumors were located in the head of pancreas in 9 cases, the neck of pancreas in 1 case and the tail of pancreas in 13 cases. There were 14 cases with abnormal tumor markers, including 6 cases with elevated NSE and 3 cases with elevated CA125. All cases were treated by surgery. Pancreatoduodenectomy was performed in 7 cases and non-pancreatoduodenectomy in 16 cases. Among the 23 patients, 2 cases were lost to follow-up, 1 case recurred and underwent reoperation, 1 case had pancreatic fistula and 1 case had gastroparesis, 6 cases were hospitalized for abdominal pain and intestinal obstruction, and no death was found in the follow-up patients.Conclusions SPTP is a rare low-grade pancreatic tumor, which is more common in female children. The typical manifestations on CT are more helpful for the diagnosis of this disease. The typical manifestations of SPTP in pathology can provide clinical guidance for diagnosis and postoperative therapy. Complete tumor resection can make patients obtain satisfactory curative effect and postoperative survival rate.
2021, Vol. 9 
