Clinical value of real-time three-dimensional transthoracic echocardiography diagnosis of cardiac rhabdomyoma in children
Niu Haiyan, Song Qing, Li Zhe, et al
1. Department of Ultrasound, the Seventh Medical Centerof Chinese PLA General Hospital, Beijing 100700, China; 2. Department of Clinical Laboratory, the SeventhMedical Center of Chinese PLA General Hospital, Beijing 100700, China
Abstract: 【Abstract】 Objective To investigate the clinical value of real-time three-dimensional transthoracic echocardiography (RT-3D-TTE) diagnosis of cardiac rhabdomyoma (CR) in children. Method From March 2016 to March 2022, 19 cases of CR diagnosed in the Seventh Medical Center of Chinese PLA General Hospital were included in this study. Among them, 15 cases were diagnosed as tuberous sclerosis (TSC). Two-dimensional transthoracic echocardiography (2D-TTE) and RT-3D-TTE were performed in all cases.The number, location, echo description, shape and size of CR lesions were recorded. The diagnostic efficiency of 2D-TTE and RT-3D-TTE was compared by the number, size and relationship with peripheral tissue of CRlesions. Statistical analysis were used by χ2 test and paired t test. Result Six cases with solitary lesion and 13 cases with multiple lesions were detected by 2D-TTE and RT-3D-TTE. In cases with multiple lesions, the numbers of lesions were 2 to 9. The total of 58 lesions were detected by 2D-TTE, while 56 lesions were detected by RT-3D-TTE. The sensitivity of RT-3D-TTE for CR is 96.5% (56/58), compared with 2D-TTE. Two moderate echo of CR lesions were not detected by RT-3D-TTE, diameters of which were less than 3 mm. There were no significant differences in locations, echo description and shape of CR lesions between RT-3DTTE and 2D-TTE (all P>0.05). The diameters of lesions detected by RT-3D-TTE were larger than that by 2D-TTE [(11.6±4.6) vs (11.2±5.1) mm], but there was no significant difference (t=0.414, P>0.05). A case with left ventricle outflow obstruction was detected by RT-3D-TTE, which was not diagnosed by 2D-TTE. In 45 lesions, RT-3D-TTE provided better views for the relationship with peripheral tissue of CR lesions, with diagnostic efficiency level A. Conclusion Application of RT-3D-TTE in the assessment of pediatric CR is feasible. RT-3D-TTE can provide more information of the spatial structure of heart, which is valuable in the diagnosis of pediatric CR.
牛海燕 宋青 李喆 李姗珊. 实时三维经胸超声心动图诊断儿童 心脏横纹肌瘤的临床价值[J]. 发育医学电子杂志, 2023, 11(2): 106-111.
Niu Haiyan, Song Qing, Li Zhe, et al. Clinical value of real-time three-dimensional transthoracic echocardiography diagnosis of cardiac rhabdomyoma in children. Journal of Developmental Medicine(Electronic Version), 2023, 11(2): 106-111.
2023, Vol. 11 
