发育医学电子杂志 Vol. 12 217-223 DOI: 10.3969/j.issn.2095-5340.2024.03.010
围产医学
综述
｜新生儿
新生儿早发型败血症的早期识别指标
孟寿东 孙群英
（德阳市罗江区人民医院 儿科，四川 罗江 618500）
Early identification indicators of neonatal early-onset sepsis
Meng Shoudong, Sun Qunying
(Department of Pediatrics, Deyang City Luojiang District People's Hospital, Sichuan, Luojiang 618500, China)
摘要 【摘要】 新生儿败血症是全球新生儿死亡的第三大原因，占新生儿总病死率的15%。早发型败血症（early-onset sepsis，EOS）大多系母体病原菌垂直传播，通常通过围产期高危因素、生后早期临床表现及 实验室检查对患儿进行综合评估，然而围产期高危因素的非特异性、临床表现的不典型性及实验室检查 的滞后性，导致早发型败血症的识别一直面临着巨大挑战。因此，本文查阅关于EOS 早期识别的最新 文献，并对相关指标进行综述，为临床早期识别EOS 提供参考。
关键词:
早发型败血症
围产期高危因素
临床表现
实验室检测
早期识别
Abstract: 【Abstract】 Neonatal sepsis is the third leading cause of neonatal death in the world, accounting for 15%of the total neonatal mortality. Most early-onset sepsis (EOS) is caused by vertical transmission of maternal pathogens, so it usually passes through the perinatal, high-risk factors, early clinical manifestations and laboratory tests are comprehensively evaluated for children. However, the non-specificity of perinatal highrisk factors, atypical clinical manifestations, and lag of laboratory tests have led to the identification of early-onset sepsis facing huge challenges. Therefore, this paper reviews the latest literature on the early identification of EOS, and reviews the relevant indicators, to provide a reference for the clinical early identification of EOS.
Key words:
Early-onset sepsis
Perinatal high-risk factor
Clinical manifestation
Laboratory test Earlyidentification
收稿日期: 2022-12-01
发布日期: 2024-05-31
通讯作者:
孙群英
E-mail: 1349823443@qq.com
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