胎儿,畸形,四维彩超,高龄孕妇 ," /> 胎儿,畸形,四维彩超,高龄孕妇 ,"/> Fetus,Malformation, Four-dimensional color ultrasound,Elderly pregnant woman ,"/> <span style="font-size:14px;line-height:2;">甘肃省部分地区胎儿结构异常的四维</span><span style="font-size:14px;line-height:2;">彩超结果分析</span><span style="font-size:14px;line-height:2;"></span>
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发育医学电子杂志  2021, Vol. 9 Issue (1): 38-42    DOI: 10.3969/j.issn.2095-5340.2021.01.007
  结构畸形   论著 |
甘肃省部分地区胎儿结构异常的四维彩超结果分析
冯淑娴 盖梅香 岳小珍 石燕
1. 解放军联勤保障部队第 940 医院 妇产科,甘肃 兰州 730050;2. 解放军第 948 医院 药剂科,新疆 乌苏 833000
The four dimensional colour result analysis of fetal structural abnormalities in parts of Gansu province
Feng Shuxian , Gai Meixiang , Yue Xiaozhen, et al
1. Department of Gynecology and Obstetrics,The 940th Hospital of Joint Logistic Support Force of Chinese PLA, Gansu, Lanzhou 730050, China; 2.Department of Pharmacy, The 948th Hospital of Chinese PLA, Xinjiang, Wusu 833000, China
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摘要 
【摘要】 目的  了解甘肃省部分地区胎儿结构异常发生率和分布情况,为本地区预防胎儿畸形和降低
出生缺陷提供理论数据。 方法 采用四维彩超标准化超声技术,对 15 135 例孕 20 ~ 26 周胎儿各系统
进行全面筛查,其中年龄 <35 岁孕妇为非高龄组(12 586 例),年龄≥ 35 岁孕妇为高龄组(2 549 例)。比较两组单发畸形和多发畸形的发生情况。采用 χ2 检验进行统计学分析。 结果  15 135 例孕妇中 262 例被检出胎儿结构异常,阳性率为 1.73%。单发畸形 237 例,其中心血管畸形(37.13%,88/237)高发,其余为颜面部畸形(18.14%,43/237)、泌尿系统畸形(13.08%,31/237)、骨骼肢体畸形(12.24%,29/237)、神经系统畸形(6.33%,15/237)、消化系统畸形和胸腹壁畸形相同均为(4.64%,11/237),少见胎儿水肿(2.11%,5/237)和腹腔占位(1.69%,4/237)。高龄组中 70 例胎儿被检出结构异常,阳性率(2.75%,70/2 549)明显高于非高龄组(1.53%,192/12 586),差异有统计学意义(χ2 =18.567,P<0.001)。25 例(9.54%,25/262)多发畸形被检出,高龄组多发畸形(11.43%,8/70)与非高龄组多发畸形(8.85%,17/192)相比,差异无统计学意义(χ2=0.394,P>0.05)。 结论 甘肃省部分地区胎儿结构异常以单发畸形为主,最高发为心脏、颜面部、泌尿系统、骨骼肢体畸形;高龄孕妇为主要分布。
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关键词:  胎儿')" href="#">    
Abstract: 
【Abstract】 Objective To detect fetal structural abnormalities in the mid-pregnancy in Lanzhou, Gansu
province, understand its incidence and distribution and provide theoretical data for preventing fetal malformations and reducing birth defects in the region. Methods Four-dimensional color Doppler ultra-standardized technology was used to comprehensively screen 15 135 cases of fetal systems at 20-26 weeks of gestation. Among them, the age <35 years old pregnant women were non-aged group (12 586 cases), and the age ≥ 35 years old pregnant women were senior group (2 549 cases). The occurrence of single and multiple malformations betweenthe two groups was compared. Statistical analysis performed by χ2 test. Results Of the 15 135 pregnant women, 262 were found to have abnormal fetal structure, with a positive rate of 1.73%. 237 cases of singlemalformation, including cardiac malformation (37.13%, 88/237), the rest of the facial deformities (18.14%,43/237), urinary malformations (13.08%, 31/237), skeletal limb deformities (12.24%, 29/237), nervous systemmalformations (6.33%, 15/237), digestive system malformations and chest and abdominal wall malformationsare the same (4.64%, 11/237), rare fetal edema (2.11%, 5/237) and the abdominal cavity occupied (1.69%,4/237). 70 cases of fetal structural abnormalities were detected in senior group, the positive rate (2.75%,70/2 549) was significantly higher than that in non-aged group (1.53%, 192/12 586), the difference wasstatistically significant (χ2 =18.567, P<0.001). 25 cases (9.54%, 25/262) of multiple malformationswere screened. There was no significant difference with multiple malformations in the senior group(11.43%, 8/70) and non-aged group (8.85%, 17/192) (χ2 =0.394,P>0.05). Conclusions The abnormal fetal structure in parts of Gansu province is mainly caused by single malformation, and the highest incidence is heart malformation, facial deformities, urinary malformations, limb malformation of bone. Elderly pregnant women are the main distribution.
Key words:  Fetus')" href="#">
收稿日期:  2019-12-17                     发布日期:  2021-01-28     
基金资助: 
兰州市科技计划资助项目(2015-2-93)
通讯作者:  盖梅香    E-mail:  815956782@qq.com
引用本文:    
冯淑娴  盖梅香  岳小珍  石燕. 甘肃省部分地区胎儿结构异常的四维彩超结果分析[J]. 发育医学电子杂志, 2021, 9(1): 38-42.
Feng Shuxian , Gai Meixiang , Yue Xiaozhen, et al.
The four dimensional colour result analysis of fetal structural abnormalities in parts of Gansu province
. Journal of Developmental Medicine(Electronic Version), 2021, 9(1): 38-42.
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http://www.fyyxzz.com/CN/10.3969/j.issn.2095-5340.2021.01.007  或          http://www.fyyxzz.com/CN/Y2021/V9/I1/38
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