发育医学电子杂志 Vol. 12 75-80 DOI: 10.3969/j.issn.2095-5340.2024.01.013
结构畸形
综述
T 淋巴细胞在胆道闭锁炎症和纤维化发生 过程中调控机制的研究进展
何峰 刘卓
首都儿科研究所 生化和免疫学研究室，北京 100020
Research progress on the regulatory mechanism of T lymphocytes during inflammation and fibrosis of biliary atresia
He Feng, Liu Zhuo
(Department of Biochemistry and Immunology, Capital Institute of Pediatrics, Beijing 100020, China)
摘要 【摘要】 胆道闭锁是以新生儿肝组织纤维化、汇管区炎症等为主要特征的疾病，围产期病毒感染被认为是致病因素之一，机体免疫调控异常在疾病进程中发挥主要作用。T 淋巴细胞在免疫调控紊乱、过强的 炎症反应以及自身抗体产生起着关键性的作用。本文对与胆道闭锁发病相关的T 淋巴细胞亚群的种类 和特点进行阐述。
关键词:
胆道闭锁
T 淋巴细胞
炎症
纤维化
调控机制
Abstract: 【Abstract】 Biliary atresia is characterized by hepatic fibrosis and inflammation in portal area of newborns,infected by virus in the perinatal period was considered to be an important cause. The abnormal immune regulation plays an important role in the process of biliary atresia, T lymphocytes plays a key role in immune disorder, severe inflammation and production of autoantibody. This article reviewed the research progress of different subtypes of T lymphocyte and their characteristic in Biliary atresia
Key words:
Biliary atresia
T lymphocyte
Inflammation
Fibrosis
Regulatory mechanism
收稿日期: 2023-04-04
发布日期: 2024-01-31
通讯作者:
刘卓
E-mail: liuzhuozhuo2005@163.com
[1]
Society of Neonatologist, Chinese Medical Doctor Association. Consensus recommendations on the prevention and early management of respiratory distress syndrome in preterm infants
[2]
Professional Committee of Respiratory, Society of Neonatologist, Chinese Medical Doctor Association. Clinical application recommendations for heated humidified high flow nasal cannula
[3]
YAN Jun, ZHU Xing-wang, SHI Yuan. Application progress of noninvasive ventilate technique for premature infants
[4]
GU Min-fang, YANG Chuan-zhong. Progress of intrapartum resuscitation for premature infants
[5]
LIU Shu-hua, SHEN Yue-bo, LIU Cui-qing, MA Li. The efficacy of pulmonary surfactant for pulmonary function in premature tension pneumothorax
[6]
GAO Xiao-hui, MAO Jian. Clinical features of non-oliguric hyperkalemia in extremely low birth weight infants
[7]
XIA Yao-fang, YANG Juan , TIAN Bao-li, et al. Value of amplitude-integrated electroencephalography in monitoring acute period of neonatal bilirubin encephalopathy and prognostic assessment
[8]
WANG Li-rong, SUN Xiao-yan, ZHU Ruo-xin, et al. Epidemiological investigation and analysis of women aged 40-55 years old with osteoporosis in Gansu province
[9]
CHEN Ru-yue, SHEN Yun-yan, CHEN Qing , et al. Five cases about Henoch-Schönlein purpura complicated with central nervous system injury in children and literatures review
[10]
ZHANG Ai-run, FANG Xiao-yi. Lung function testing of bronchopulmonary dysplasia for infants and children
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2024, Vol. 12 
