发育医学电子杂志 Vol. 5 209-211
生长发育
专题笔谈
吸入性糖皮质激素长期控制支气管哮喘对儿童生长的影响
刘长山
天津医科大学第二医院 儿科，天津 300211
Influence of inhaled corticosteroids for long-term control of bronchial asthma on growth and development of children
LIU Chang-shan
摘要 支气管哮喘（简称哮喘）是儿童时期最常见的慢性气道疾病，是一种以慢性气道炎症和气道高反应性为特征的异质性疾病，临床以反复发作的喘息、咳嗽、气促、胸闷为主要表现，常在夜间和（或）凌晨发作或加剧。近年来，我国儿童哮喘的患病率呈明显上升趋势，1990年、2000年和2010年3次全国城市14岁以下儿童哮喘流行病学调查显示，累积患病率分别为1.09%、1.97%和3.02%。我国的儿童哮喘防治指南根据临床表现将哮喘分为急性发作期、慢性持续期和临床缓解期。哮喘的治疗包括快速缓解治疗和长期控制治疗两部分。急性发作期主要采取以平喘、抗炎治疗为主的快速缓解治疗；慢性持续期和临床缓解期，采取避免触发因素、抗炎、降低气道高反应性、防止气道重塑的措施，并做好自我管理的长期控制治疗，以防止哮喘症状加重和预防哮喘复发。国内外哮喘防治指南均明确指出，治疗中，吸入性糖皮质激素（inhaled corticosteroids，ICS）是哮喘长期控制的基石。在重视ICS带来临床获益的同时，人们也越来越关注其长期应用的安全性，尤其是对儿童生长的影响。
关键词:
吸入性糖皮质激素
支气管哮喘
儿童
生长发育
收稿日期: 2017-09-04
出版日期: 2017-10-30
发布日期: 2018-01-23
期的出版日期: 2017-10-30
基金资助: 天津市卫生行业重点攻关项目（16KG116）
通讯作者:
刘长山：http://www.yd2y.com.cn/Html/Doctors/Main/Detail_119.html
E-mail: chshliu@163.com
作者简介: 刘长山：http://www.yd2y.com.cn/Html/Doctors/Main/Detail_119.html
引用本文:
刘长山. 吸入性糖皮质激素长期控制支气管哮喘对儿童生长的影响 [J]. 发育医学电子杂志, 2017, 5(4): 209-211.
Influence of inhaled corticosteroids for long-term control of bronchial asthma on growth and development of children . Journal of Developmental Medicine(Electronic Version), 2017, 5(4): 209-211.
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