发育医学电子杂志 2022, Vol. 10 Issue (2): 156-160 DOI: 10.3969/j.issn.2095-5340.2022.02.014
临床遗传
综述
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产前应用糖皮质激素对子代神经发育 影响的研究进展
李宇丹 李冬
大连市妇女儿童医疗中心 新生儿科,辽宁 大连 116037
Effect of antenatal corticosteroids on the neurodevelopment of offspring
Li Yudan, Li Dong
摘要 产前应用糖皮质激素(antenatal corticosteroids, ACS)能够促进胎肺成熟,减少早产儿出生后早期 呼吸系统并发症,提高早产儿存活率,目前已被广 泛用于临床。自20 世纪70 年代至今,ACS 在全 世界范围内得以广泛应用,已证明在降低多种早产 儿并发症中发挥了显著作用[1-2 ]。随着早产儿发病 率及存活率的提高和出院后健康随访管理的建立, ACS 应用关于子代远期神经行为发育影响的研究 逐渐引起关注,目前关于其应用的胎龄、药物种类 及疗程的选择对神经系统发育的影响存在争议。
关键词:
糖皮质激素类
早产
婴儿
预后
神经行为发育
收稿日期: 2021-01-24
发布日期: 2022-03-31
通讯作者:
李冬
E-mail: dongli@dmu.edu.cn
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