发育医学电子杂志 2023, Vol. 11 Issue (4): 308-315 DOI: 10.3969/j.issn.2095-5340.2023.04.011 |
综述
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补救胞浆内单精子注射受精失败的原因分析 |
任晶辉 土增荣 高瑞璠 |
1. 山西医科大学 第一临床医学院,山西 太原030000 ;2. 山西医科大学第一医院 生殖中心,山西 太原 030000
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Analysis of reasons for the fertilization failure of rescue intracytoplasmic sperm injection |
Ren Jinghui, Tu Zengrong, Gao Ruifan |
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摘要 全世界1.86 亿人患有不孕症,育龄夫妇占8%~12%,且发病率逐年增加[1]。体外受精(in vitro fertilization,IVF)与胞浆内单精子注射(intracytoplasmic sperm injection,ICSI)是目前最常用且有效的辅助生殖技术(assisted reproductivetechnology,ART),为不孕夫妇带来希望。遗憾的是,即使IVF 技术日益完善,完全受精失败的风险仍不可避免,其发生率为 5%~20 %[ 2-3]。早期补救胞浆内单精子注射(rescue intracytoplasmic sperminjection,r-ICSI)的出现,可以在不取消ART 周期的情况下,直接对IVF未受精的卵母细胞进行补救,避免了周期的取消以及完全受精失败的发生,使经济成本下降了25%,也缓解了患者的精神压力[4-5]
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关键词:
补救胞浆内单精子注射
r-ICSI
ICSI
卵母细胞老化
卵母细胞激活
基因突变
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收稿日期: 2022-09-16
出版日期: 2023-07-31
发布日期: 2023-07-31
期的出版日期: 2023-07-31
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通讯作者:
土增荣
E-mail: sxtytzr@126.com
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[1] |
Society of Neonatologist, Chinese Medical Doctor Association. Consensus recommendations on the prevention and early management of respiratory distress syndrome in preterm infants[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 129
-131
. |
[2] |
Professional Committee of Respiratory, Society of Neonatologist, Chinese Medical Doctor Association. Clinical application recommendations for heated humidified high flow nasal cannula[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 132
-135
. |
[3] |
YAN Jun, ZHU Xing-wang, SHI Yuan. Application progress of noninvasive ventilate technique for premature infants[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 136
-140
. |
[4] |
GU Min-fang, YANG Chuan-zhong. Progress of intrapartum resuscitation for premature infants[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 141
-145
. |
[5] |
LIU Shu-hua, SHEN Yue-bo, LIU Cui-qing, MA Li. The efficacy of pulmonary surfactant for pulmonary function in premature tension pneumothorax[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 146
-151
. |
[6] |
GAO Xiao-hui, MAO Jian. Clinical features of non-oliguric hyperkalemia in extremely low birth weight infants[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 152
-158
. |
[7] |
XIA Yao-fang, YANG Juan , TIAN Bao-li, et al. Value of amplitude-integrated electroencephalography in monitoring acute period of neonatal bilirubin encephalopathy and prognostic assessment[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 159
-163
. |
[8] |
WANG Li-rong, SUN Xiao-yan, ZHU Ruo-xin, et al. Epidemiological investigation and analysis of women aged 40-55 years old with osteoporosis in Gansu province[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 164
-167
. |
[9] |
CHEN Ru-yue, SHEN Yun-yan, CHEN Qing , et al. Five cases about Henoch-Schönlein purpura complicated with central nervous system injury in children and literatures review[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 168
-171
. |
[10] |
ZHANG Ai-run, FANG Xiao-yi. Lung function testing of bronchopulmonary dysplasia for infants and children[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 172
-176
. |
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