发育医学电子杂志 2021, Vol. 9 Issue (3): 169-175 DOI: 10.3969/j.issn.2095-5340.2021.03.002
围产医学
专题笔谈
|新生儿
|
预防新生儿早发型B 族溶血性链球菌 感染新策略
祝垚 林新祝
厦门市妇幼保健院 厦门大学附属妇女儿童医院 新生儿科 厦门市围产- 新生儿感染重点实验室,福建 厦门 361003
New strategy for preventing group B streptococcus early onset infection in neonates
Zhu Yao, Lin Xinzhu
摘要 B 族溶血性链球菌(group B Streptococcus, GBS)是引起羊膜腔内感染和早发型新生儿感染的
主要病原菌。由于围产期GBS 感染死亡率高、危害 大,自20 世纪70 年代以来西方国家对其预防和处
理给予了高度重视。1996 年美国疾病预防控制中 心(centers for disease control and prevention, CDC)
针对围产期GBS 的防治制订了规范化方案[1] ,随 后于2002 年和2010 年进行了两次修订[2-3] ,随着
预防与治疗指南的不断更新,美国新生儿早发型 GBS 疾病(GBS early-onset disease,GBS-EOD)发生
率从1990 年的1.8/1 000 个活产婴下降到2015 年 的0.23/1 000 个活产婴,降幅达80%[4-5] 。2019 年
6 月和2020 年2 月由美国妇产科协会(American College of Obstetricians and Gynecologists, ACOG)先
后两次对指南进行更新(782 和797 号文件)[6-7] , 2019 年7 月美国儿科协会(American Academy of
Pediatrics, AAP)也做出新生儿GBS 感染的风险管 理[5] ,以上方案作为预防围产期GBS 感染的最新
临床指导。
关键词:
新生儿')" href="#">新生儿
B族溶血性链球菌
筛查')" href="#"> 筛查
收稿日期: 2021-02-18
发布日期: 2021-05-26
基金资助: 福建省科技计划引导性项目(2018D0011);厦门市科技计划重大专项立项(3502Z20171006)
通讯作者:
林新祝
E-mail: xinzhufj@163.com
[1]
Society of Neonatologist, Chinese Medical Doctor Association. Consensus recommendations on the prevention and early management of respiratory distress syndrome in preterm infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 129
-131
.
[2]
Professional Committee of Respiratory, Society of Neonatologist, Chinese Medical Doctor Association. Clinical application recommendations for heated humidified high flow nasal cannula [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 132
-135
.
[3]
YAN Jun, ZHU Xing-wang, SHI Yuan. Application progress of noninvasive ventilate technique for premature infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 136
-140
.
[4]
GU Min-fang, YANG Chuan-zhong. Progress of intrapartum resuscitation for premature infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 141
-145
.
[5]
LIU Shu-hua, SHEN Yue-bo, LIU Cui-qing, MA Li. The efficacy of pulmonary surfactant for pulmonary function in premature tension pneumothorax [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 146
-151
.
[6]
GAO Xiao-hui, MAO Jian. Clinical features of non-oliguric hyperkalemia in extremely low birth weight infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 152
-158
.
[7]
XIA Yao-fang, YANG Juan , TIAN Bao-li, et al. Value of amplitude-integrated electroencephalography in monitoring acute period of neonatal bilirubin encephalopathy and prognostic assessment [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 159
-163
.
[8]
WANG Li-rong, SUN Xiao-yan, ZHU Ruo-xin, et al. Epidemiological investigation and analysis of women aged 40-55 years old with osteoporosis in Gansu province [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 164
-167
.
[9]
CHEN Ru-yue, SHEN Yun-yan, CHEN Qing , et al. Five cases about Henoch-Schönlein purpura complicated with central nervous system injury in children and literatures review [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 168
-171
.
[10]
ZHANG Ai-run, FANG Xiao-yi. Lung function testing of bronchopulmonary dysplasia for infants and children [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 172
-176
.
Viewed
Full text
Abstract
Cited
Shared
Discussed