Influence of duration of umbilical venous catheterization on critically ill neonatal complications
Guo Ming, Jiao Mingyue, Shang Zhizhong,et al
1.Department ofPediatrics, the Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China; 2. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Gansu, Lanzhou 730000,China; 3. the Second Clinical Medical School, Lanzhou University, Gansu, Lanzhou 730000, China
Abstract: 【Abstract】 Objective To explore the effects of umbilical venous catheterization (UVC) duration on critically ill neonatal infections and other related complications. Method A total of 180 critically ill newborns in the Pediatric Department, the Fifth Medical Center of Chinese PLA General Hospital from March2017 to March 2020 with birth weight of less than 1 800 g, persistent hypoglycemia or severe asphyxia wereselected and divided into control group (duration of UVC ≤ 7 d, n=74) and observation group (duration ofUVC>7 d, n=106) . The infection-related indicators (abnormal infection index within 3 days of tube withdrawalusing of antibiotic after 7 days, positive blood culture), situation of tube end culture bacteria and gastricretention, abdominal bloating, vomiting, neonatal necrotizing enterocolitis (NEC), omphalitis, thrombosis,liver complications, thoracic peritoneal and pericardial effusion, intravenous nutrition time, full feedingtime, and the hospital stays were compared. t test and χ2 test were used for statistical analysis. ResultAbnormal infection index within 3 days of tube withdrawal in the observation group was 26 cases (24.5%)and 13 cases (17.6%) in the control group, with no statistical significance (χ2=1.473, P>0.05). After 7 daysof catheterization, 30 cases (28.3%) in the observation group received antibiotic, while 18 cases (24.3%) inthe control group received antibiotic, with no statistical significance (χ2=0.801, P>0.05). There were 3 cases(2.8%) of positive blood culture in the observation group and 2 cases (2.7%) in the control group, with nostatistically significant (χ2=0.052, P>0.05). And no bacteria were cultured in the tube ends of the two groups.There were no thrombosis, liver complications, thoracic peritoneal and pericardial effusion in both groups.Also there was no statistically significant difference between the two groups in gastric retention, abdominalbloating, vomiting, neonatal NEC, omphalitis, intravenous nutrition time, feeding full time, or hospital stays( all P>0.05). Conclusion Compared with short-term use of UVC, prolonging UVC for more than 7 daysdoes not increase the risk of infection and other complications, so we can appropriately prolong the durationof UVC to provide nutritional support and treatment for critically ill newborns.
2022, Vol. 10 
