The physical and neuropsychological development of hospitalized premature infants at the adjusted age of 1 year and the influencing factors
Yuan Li, Xia Rongming, Gao Yueqiao, et al
1.Department of Child Healthcare, Beijing Chaoyang District Maternal and Child Health Hospital, Beijing 100021, China; 2.Department of Stomatology, Beijing Chaoyang District Maternal and Child Health Hospital, Beijing 100021, China; 3.Department of Pediatrics, Beijing Chaoyang District Maternal and Child Health Hospital, Beijing 100021, China; 4.Department of Pediatrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100020, China
Abstract: 【Abstract】 Objective To analyze the physical and neuropsychological development of hospitalized premature infants at the adjusted age of 1 year and the influencing factors of catch-up growth. MethodsFrom January 1, 2017 to June 30, 2019, 450 hospitalized premature infants and 200 healthy full-term infants who born in Beijing Chaoyang District Maternal and Child Health Hospital were selected as the research subjects. The physical and neuropsychological development of the two groups at the adjusted age of 1 year were compared. The preterm infants were divided into the weight catch-up growth satisfaction group (360 cases) and dissatisfaction group (90 cases), development quotient normal group (373 cases) and development low group (77 cases) according to their development status. The influencing factors of weight catch-up growth and development of preterm infants at the adjusted age of 1 year were analyzed. Statistical analysis was performed using t test, χ2 test and Logistic regression analysis. Results The height [(74.7±2.1) vs (75.1±2.3) cm], weight [(9.7±1.1) vs (10.0±1.2) kg], head circumference [(45.0±1.5) vs (45.3±1.6) cm] and developmental quotient of preterm infants at the adjusted age of 1 year were significantly lower than those of full-term infants (P<0.05). The gestational age at birth <32 weeks, daily milk intake below normal (OR=2.665, 95%CI: 1.318-5.389), early birth with digestive abnormalities (OR=3.615, 95%CI: 1.680-7.779) and high nutritional risk at discharge (OR=4.194, 95%CI:1.782-9.867) were independent risk factors of unsatisfactory growth effect of catch-up for premature infants at adjusted age of 1 year. Low birth weight (OR=2.628, 95%CI: 1.474-4.687), early birth with neurological damage (OR=3.208, 95%CI: 1.573-6.544) were independent risk factors of low developmental quotient for preterm infants at adjusted age of 1 year, and receiving developmental training(OR=0.497, 95%CI: 0.295-0.838) was a protective factor. Conclusions The physical and neuropsychological development of preterm infants at adjusted age of 1 year are weaker than those of full-term infants. Catch-up growth is mainly affected by gestational age, birth weight, birth complications and other factors, reasonable intervention can reduce the risk of underdevelopment.
袁丽 夏荣明 高月乔 王璟 李秋菊. 住院早产儿校正年龄1 岁时体格和神经心理发育情况及影响因素分析[J]. 发育医学电子杂志, 2022, 10(1): 38-44.
Yuan Li, Xia Rongming, Gao Yueqiao, et al. The physical and neuropsychological development of hospitalized premature infants at the adjusted age of 1 year and the influencing factors. Journal of Developmental Medicine(Electronic Version), 2022, 10(1): 38-44.
2022, Vol. 10 
