【Abstract】 Objective To explore the improvement effect of routine comprehensive nursing treatmentcombined with physical intervention on feeding quality of premature infants. Methods From December2018 to July 2019, 102 premature infants admitted to the neonatal intensive care unit of Affiliated Hospitalof Qingdao University were included in the study, and they were randomly divided into an interventiongroup of 52 infants and a control group of 50 infants. All the premature babies were fed with gravitytube every 3 hours. Control group were performed routine comprehensive nursing and oral care. In theintervention group, physical intervention measures were added, including colostrum oral care, oral motorintervention and abdominal massage, for a total of 10 days. Changes in feeding quality and feedingprocess were recorded and analyzed in the two groups after intervention. Then t-test and χ2 test wereused for statistical analysis. Results ① Basic situation: There was no significant difference betweenthe intervention group and the control group in terms of gestational age, gender, birthweight,ventilatoryassistedventilation, maternal diseases, prenatal hormone use and defecation frequency in the first week after
birth (P>0.05). ② Feeding quality: On first day of the study, there was no statistically significant difference
in abdominal circumference, vomiting frequency, gastric retention and body weight between the intervention
group and the control group (P>0.05). On the 10th day of the study, the body weight and milk volume of the
children in the intervention group were higher than those in the control group [body weight (1 775±401) and
(1 563±336) g, milk volume (91±43) and (73±46) ml/(kg·d), P<0.05]; and the abdominal circumference
and gastric retention of the intervention group were lower than those in the control group [abdominal
circumference (23.7±2.1) and (24.6±2.2) cm, gastric retention (2.8±2.2) and (4.9±1.9) ml, P<0.05].
③ Feeding process: The initial oral feeding time and tube feeding time of preterm infants in the intervention
group were lower than those in the control group [initial oral feeding time (11.5±10.0) and (18.5±15.0) d,
tube feeding time (18±15) and (26±17) d, P<0.05]. Conclusion Physical interventions such as colostrum
immunotherapy, oral motor intervention and abdominal massage can improve the feeding quality, shorten the
tube feeding time, promote the feeding process and improve the prognosis of premature infants.