Abstract: 【Abstract】 Objective To explore the high-risk factors of premature respiratory failure. Methods Between January 1st 2013 and December 31st 2014, there were 1 136 premature infants born in Department of Obstetrics of Liaocheng People's Hospital, 501 cases in respiratory failure group, 635 cases in control group. The general condition, delivery condition, 1 minute and 5 minutes Apgar score and mother condition and other factors of both groups were compared. Chi-square test was used for the single factor analysis group comparison. Multivariate Logistic regression analysis was performed with premature respiratory failure as a dependent variable and indicators of statistical significance in single factor analysis as the independent variable. Results Among the 1 136 premature infants, respiratory failure cases accounted for 44.1% (501/1 136), and 332 cases were male (66.3%, 332/501). The average gestational age was (34.05±2.11) weeks and the average birth weight was (2 129±585) g. Ten factors include gender, gestational age, birth weight, 1 minute and 5 minutes Apgar score, delivery mode, prenatal hormone, prenatal fever, placental abruption and placenta previa were associated with premature respiration failure (P ﹤0.05). Parity, whether the prenatal hormone was used enough, premature rupture of membranes, amniotic fluid contamination, umbilical cord around the neck, gestational diabetes and gestational hypertension disease were no significant correlation with premature respiratory failure (P ﹥ 0.05). The result of multivariate Logistic regression analysis showed that the male, gestational age ﹤ 34 weeks (especially ﹤ 32 weeks), low birth weight, Apgar score ≤ 7 points (especially 5 minutes Apgar score), cesarean section and placenta previa were high-risk factors of premature respiratory failure (P ﹤ 0.05). Prenatal fever of pregnant woman is the protective factor for premature respiration failure. Conclusion For the premature infants with high-riskfactors, respiratory support and other treatment should be given timely, in order to prevent the occurrence of premature respiratory failure.
2018, Vol. 6 
