三亚市孕妇缺铁性贫血与抑郁症的相关性研究

doi:10.3969/j.issn.2095-5340.2023.01.007

发育医学电子杂志

2023, Vol. 11

Issue (1): 38-43 DOI: 10.3969/j.issn.2095-5340.2023.01.007

围产医学论著｜产科

三亚市孕妇缺铁性贫血与抑郁症的相关性研究

黄颀　曾祥丽

上海儿童医学中心三亚市妇女儿童医院　妇女保健科，海南三亚　 572000

Study on the relationship between iron deficiency anemia and depression in pregnant women in Sanya city

Huang Qi, Zeng Xiangli

Department of Women's Health Care, Sanya Women and Children's HospitalManaged by Shanghai Children’s Medical Center, Hainan, Sanya 572000, China

摘要
相关文章
推荐阅读
Metrics

下载:

PDF (958KB)
输出: BibTeX | EndNote (RIS)

摘要 【摘要】目的　探讨孕妇缺铁性贫血（ iron deiciency anemia，IDA）与抑郁症之间的相关性。　方法　纳
入2020 年1 月至2021 年12 月在三亚市妇女儿童医院进行产前检查、资料完整的孕妇共2 571 例为研究对象。分为IDA 组和非IDA 组，并对孕妇进行抑郁状态评估。比较IDA 组和非IDA 组、抑郁症组和非抑郁症组的特征。统计学方法采用t 检验、χ2 检验、多元逐步Logistic 回归分析。　结果2 571 例孕妇中，561 例孕妇确诊为IDA，2 010 例为非IDA。IDA 组产次≥ 1 次的孕妇比例（22.99%，129 /561）明显低于非IDA 组（28.01%，563/2 010），两组之间差异具有统计学意义（P<0.05）；两组之间在年龄、所在地区、教育水平、工作状况、主动或被动吸烟情况、流产史以及合并疾病情况等方面比较差异均无统计学意（P>0.05）。在纳入的研究对象中，232 例孕妇（232/2 571，9.02%）存在抑郁症，抑郁症组IDA 孕妇明显高于非抑郁症组，两组间比较差异具有统计学意义［30.17%（70/232）与 20.99%（491/2 339），P=0.001］，IDA 程度在两组间差异也具有统计学意义（P=0.006）。多元逐步Logistic 回归分析结果显示，IDA（OR=2.717，95%CI ：1.301~3.987，P=0.011）、贫血程度（OR=1.227，95%CI ：1.035~1.452，P=0.020）、无业/ 待业（OR=4.151，95%CI ：1.283~10.297，P=0.006）、流产史（OR=1.005，95%CI ：1.001~1.010，P=0.017）、人工助孕（OR=1.471，95%CI：1.133~1.897，P=0.004）以及合并其他疾病（OR=5.032，95%CI：1.533~13.472，P=0.006）为孕妇抑郁症的危险因素。结论　IDA 为孕妇发生抑郁症的危险因素，应进行治疗及心理干预，以改善妊娠结局。

	服务
	把本文推荐给朋友
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章

关键词: 缺铁性贫血抑郁症孕妇流产人工助孕

Abstract: 【Abstract】 Objective To investigate the relationship between iron deficiency anemia (IDA) anddepression in pregnant women.　Method　The study included 2 571 pregnant women who had completedprenatal examination and information in Sanya Women and Children's Hospital from January 2020 toDecember 2021. The cases were divided into IDA group and non-IDA group, and the depression status ofpregnant women was evaluated. The characteristics of IDA group and non-IDA group and depression andnon-depression groups were compared. The statistical method was t test, χ2 test, and multiple stepwiseLogistic regression analysis.　Result　Of 2 571 pregnant women, 561 cases were diagnosed as IDAand 2 010 cases were diagnosed as non-IDA. 22.99% (129/561) of Pregnant women with ≥1 birth in IDAgroup were significantly lower than 28.01% (563/2 010) in non-IDA group, which was statistical significance(P<0.05). There were no significant differences between the two groups in terms of age, location, educationlevel, work status, active or passive smoking, history of miscarriage, and comorbid diseases (P>0.05). Amongthe included cases, 232 pregnant women (232/2 571, 9.02%) had depression, and IDA in the depressedgroup was higher than that in the non-depressed group, with statistical significance [30.17% (70/232) vs20.99% (491/2 339), P=0.001]. There was also a statistically significant difference in IDA between the twogroups (P=0.006). Multivariate stepwise Logistic regression analysis showed that IDA (OR=2.717, 95%CI:1.301-3.987, P=0.011), the degree of the anemia (OR=1.227, 95%CI: 1.035-1.452, P=0.020), unemployed(OR=4.151, 95%CI: 1.283-10.297, P=0.006), history of miscarriage (OR=1.005, 95%CI: 1.001-1.010,P=0.017), assisted reproductive technologies (OR=1.471, 95%CI: 1.133-1.897, P=0.004) and concomitantother diseases (OR=5.032, 95%CI: 1.533-13.472, P=0.006) were risk factors for the occurrence of depressionin pregnant women.　Conclusion　 IDA is a risk factor for depression in pregnant women. Treatment andpsychological intervention should be carried out to improve the pregnancy outcome

Key words: Iron deficiency anemia Depression Pregnant women Miscarriage Artificial assisted pregnancy

收稿日期: 2022-06-20 发布日期: 2023-01-30

基金资助: 海南省临床医学中心建设项目（2021-276）

通讯作者: 曾祥丽 E-mail: 515384471@qq.com

引用本文:

黄颀　曾祥丽. 三亚市孕妇缺铁性贫血与抑郁症的相关性研究[J]. 发育医学电子杂志, 2023, 11(1): 38-43.
Huang Qi, Zeng Xiangli. Study on the relationship between iron deficiency anemia and depression in pregnant women in Sanya city. Journal of Developmental Medicine(Electronic Version), 2023, 11(1): 38-43.

链接本文:

http://www.fyyxzz.com/CN/10.3969/j.issn.2095-5340.2023.01.007 或 http://www.fyyxzz.com/CN/Y2023/V11/I1/38

[1]	辛亚维　王龙斌　张步美　王建梅　顾艳. MicroRNA 在胎盘发育及复发性流产中的研究进展[J]. 发育医学电子杂志, 2023, 11(1): 60-64.
[2]	张惠　栾俊　李艳　霍杉杉　窦娜. 产前吸奶器干预泌乳对产后母乳喂养质量的影响[J]. 发育医学电子杂志, 2023, 11(1): 25-31.
[3]	吕嬿　戚庆炜　蒋宇林　周希亚　郭琦　郝娜　常家桢　刘俊涛. 高龄孕妇胎儿染色体非整倍体产前筛查和产前诊断的卫生经济学分析[J]. 发育医学电子杂志, 2022, 10(5): 321-329.
[4]	靳元元　李铭德　刘洋　张建军. p53 基因介导的细胞凋亡与复发性流产的研究进展[J]. 发育医学电子杂志, 2022, 10(4): 315-320.
[5]	王玲　李燕滨　陈锦红　吴涢婷　朱红梅. 高龄孕妇妊娠早期外周血自然杀伤细胞与先兆流产的相关性研究[J]. 发育医学电子杂志, 2021, 9(6): 443-448.
[6]	赵旭亮　张曼　田瑞霞　崔智慧　汪鹏程. 高通量测序联合染色体核型检测筛查高龄孕妇胎儿发育畸形的实践研究[J]. 发育医学电子杂志, 2021, 9(6): 449-454.
[7]	梁建梅　卢雪景　刘晓旭　秦丽欣　王亚凡. 甲状腺自身抗体阳性对复发性流产的临床意义[J]. 发育医学电子杂志, 2021, 9(5): 341-345.
[8]	金珈汐　孙静莉. 全面二孩政策实施前后的产妇特征及剖宫产指征分析[J]. 发育医学电子杂志, 2021, 9(5): 353-358.
[9]	卢雪景　梁建梅　申林林　白娅琴　秦丽欣　高金霞　王亚凡. 低分子肝素联合小剂量阿司匹林对复发性流产患者血栓前状态、肝功能及免疫功能的影响[J]. 发育医学电子杂志, 2021, 9(3): 214-219.
[10]	伍丽婷　薛佳　李诗萌　袁正伟. 孕妇不同孕周血清碱性磷酸酶变化规律的队列研究[J]. 发育医学电子杂志, 2021, 9(1): 43-48.
[11]	冯淑娴　盖梅香　岳小珍　石燕. 甘肃省部分地区胎儿结构异常的四维彩超结果分析[J]. 发育医学电子杂志, 2021, 9(1): 38-42.
[12]	刘盾关怀尚丽新. 复发性流产免疫学病因及诊治进展[J]. 发育医学电子杂志, 2019, 7(1): 55-59.
[13]	刘盾　关怀. 复发性流产的病因及治疗进展[J]. 发育医学电子杂志, 2018, 6(4): 208-212.
[14]	于若寒　孙琳　刘湘源. 产科抗磷脂综合征与复发性流产的研究进展[J]. 发育医学电子杂志, 2017, 5(2): 122-125.
[15]	马妍　李文. 早期自然流产绒毛发育影响因素的研究进展[J]. 发育医学电子杂志, 2016, 4(1): 57-61.

[1]	Society of Neonatologist, Chinese Medical Doctor Association. Consensus recommendations on the prevention and early management of respiratory distress syndrome in preterm infants[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 129 -131 .
[2]	Professional Committee of Respiratory, Society of Neonatologist, Chinese Medical Doctor Association. Clinical application recommendations for heated humidified high flow nasal cannula[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 132 -135 .
[3]	GU Min-fang, YANG Chuan-zhong. Progress of intrapartum resuscitation for premature infants[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 141 -145 .
[4]	LIU Shu-hua, SHEN Yue-bo, LIU Cui-qing, MA Li. The efficacy of pulmonary surfactant for pulmonary function in premature tension pneumothorax[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 146 -151 .
[5]	GAO Xiao-hui, MAO Jian. Clinical features of non-oliguric hyperkalemia in extremely low birth weight infants[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 152 -158 .
[6]	XIA Yao-fang, YANG Juan , TIAN Bao-li, et al. Value of amplitude-integrated electroencephalography in monitoring acute period of neonatal bilirubin encephalopathy and prognostic assessment[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 159 -163 .
[7]	WANG Li-rong, SUN Xiao-yan, ZHU Ruo-xin, et al. Epidemiological investigation and analysis of women aged 40-55 years old with osteoporosis in Gansu province[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 164 -167 .
[8]	CHEN Ru-yue, SHEN Yun-yan, CHEN Qing , et al. Five cases about Henoch-Schönlein purpura complicated with central nervous system injury in children and literatures review[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 168 -171 .
[9]	ZHANG Ai-run, FANG Xiao-yi. Lung function testing of bronchopulmonary dysplasia for infants and children[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 172 -176 .
[10]	LI Qiu-yu, LI Lu-quan. Risk factors and predictors for aggravation of neonatal necrotizing enterocolitis[J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 177 -180 .

Viewed

Full text

Abstract

Cited

Shared

Discussed