Clinical analysis of term premature rupture of membranes and perinatal outcomes
Qiao Yanxia, Cao Xinghua, Chen Xinyu, et al
(1. Department of Neonatology,Shijiazhuang Obstetrics and Gynecology Hospital, Hebei, Shijiazhuang 050035, China; 2. Beijing KeyLaboratory of Pediatric Organ Failure, National Engineering Laboratory for Birth defects prevention andcontrol of key technology, Institute of Pediatrics, the Seventh Medical Center of PLA General Hospital,Faculty of Pediatrics, the Chinese PLA General Hospital, Beijing 100700, China
Abstract: 【Abstract】 Objective To investigate the clinical characteristics of term premature rupture of membranes(PROM) and perinatal outcomes. Method A total of 332 cases of PROM with gestational weeks of37-41+6 in Shijiazhuang Obstetrics and Gynecology Hospital from September 2017 to January 2018 wereselected as the PROM group. 332 cases were matched with the PROM group according to the parturient age,gestational weeks and delivery time as the control group. Mothers and their neonates were followed up to7 days after birth. The characteristics of maternal history, as well as maternal, fetal and neonatal outcomeswere compared between the two groups. Statistical methods performed by t test, χ2 test or Fisher's probabilitymethod. Result There was no significant difference in the gestational age, birth weight or gender ofneonates between the PROM group and the control group (all P>0.05). The proportion of primiparas in thePROM group was higher than that of the control group (72.59% vs 52.11%, χ2=58.438, P<0.001). The rateof induced labor in the PROM group was higher than that in control group (9.34% vs 2.11%, χ2=16.078,P<0.001), while the cesarean section rate was lower than that in control group (12.95% vs 32.53%, χ2=36.216,P<0.001). There was no statistically significant difference in clinical chorioamnionitis between thePROM group and the control group, but the incidence of histopathological chorioamnionitis wassignificantly higher than that of control group (17.17% vs 1.51%, χ2=48.105, P<0.001). The incidence ofneonatal infection in the PROM group was higher than that in control group (2.99% vs 0.60%, χ2=5.407,P<0.05). Conclusion For pregnancies, primiparas should pay more attention to the occurrenceof PROM. In addition, PROM may increase the risk of neonatal infection. To reduce parturient andinfant complications and improve neonatal survival rate, we should refer to the published guidelines andintervene actively in the treatment process.
2022, Vol. 10 
