发育医学电子杂志 2022, Vol. 10 Issue (4): 310-314 DOI: 10.3969/j.issn.2095-5340.2022.04.011
围产医学
综述
|新生儿
|
新生儿坏死性小肠结肠炎生物标记物的 研究进展
司乐羽 史源
重庆医科大学附属儿童医院 新生儿科 儿童发育疾病研究教育部 重点实验室 国家儿童健康与疾病临床医学研究中心 儿童发育重大疾病国家国际 科技合作基地 儿科学重庆市重点实验室,重庆 400014
Research progress of biomarkers of neonatal necrotizing enterocolitis
Si Leyu, Shi Yuan
摘要 坏死性小肠结肠炎(necrotizing enterocolitis, NEC)是早产儿中常见的严重肠道炎性疾病,与早 产、感染、缺氧及肠道菌群失调等有关,发病率、病 死率高,即使存活的患儿后期也可能会出现严重的 后遗症,包括短肠综合征、胆汁淤积和神经发育迟 缓等 [1-2] 。 近年来,新生儿科诊疗技术进展迅速, 更多的极早产儿、极低出生体质量儿得以存活,但 NEC 的发病率呈上升趋势 [3] 。
关键词:
坏死性小肠结肠炎
新生儿
生物标志物
收稿日期: 2022-01-10
发布日期: 2022-07-31
基金资助: 国家重点研发计划 (2019YFC0840703);中央引导地方科技发展基金专项(2019-2020);重庆市 技术创新与应用发展专项大健康领域重点研发项目(CSTC2021jscx-gksb-N0015)
通讯作者:
史源
E-mail: shiyuan@hospital.cqmu.edu.cn
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