发育医学电子杂志 2023, Vol. 11 Issue (4): 301-307 DOI: 10.3969/j.issn.2095-5340.2023.04.010
结构畸形
综述
|
胆道闭锁无创整合诊断的研究进展
吉泽 刘晓书 任红霞
1. 山西医科大学 儿科医学系,山西 太原 030000 ;2. 山西省儿童医院 新生儿外科,山西 太原 030000
Research progress in noninvasive and integrated diagnosis of biliary atresia
Ji Ze, Liu Xiaoshu, Ren Hongxia
摘要 胆道闭锁是新生儿梗阻性黄疸的最常见原因, 是一种以肝内外胆管炎症和进行性肝纤维化为特 征的严重肝胆疾病,很多患儿最终需要接受肝移 植治疗。早期行肝门空肠吻合术可显著改善近期 预后,否则会丧失最佳治疗时机或很快发展为终 末期肝病,导致不得不提早行肝移植。因此胆道 闭锁的尽早诊断、及时治疗对提高患儿自体肝生 存率极其重要。目前术中胆管造影及肝组织病理 活检是公认的胆道闭锁诊断金标准,但该诊断方 法不仅有创,而且常需要经验丰富的小儿外科和 病理科医师才能做出判断,不是临床早期诊断的 首选。因此寻找简单易行、方便可靠、可定量化的 早期诊断方法一直是业界不断探寻的目标。本文 围绕近年来胆道闭锁早期临床筛查、无创整合诊 断进行综述,以期为胆道闭锁患儿早期临床决策 提供帮助。
关键词:
胆道闭锁
诊断
无创
整合
收稿日期: 2023-04-04
出版日期: 2023-07-31
发布日期: 2023-07-31
期的出版日期: 2023-07-31
基金资助: 山西省卫生与健康委员会科研课题(2022074)
通讯作者:
任红霞
E-mail: renhongxia100@sina.com
[1]
Society of Neonatologist, Chinese Medical Doctor Association. Consensus recommendations on the prevention and early management of respiratory distress syndrome in preterm infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 129
-131
.
[2]
Professional Committee of Respiratory, Society of Neonatologist, Chinese Medical Doctor Association. Clinical application recommendations for heated humidified high flow nasal cannula [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 132
-135
.
[3]
YAN Jun, ZHU Xing-wang, SHI Yuan. Application progress of noninvasive ventilate technique for premature infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 136
-140
.
[4]
GU Min-fang, YANG Chuan-zhong. Progress of intrapartum resuscitation for premature infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 141
-145
.
[5]
LIU Shu-hua, SHEN Yue-bo, LIU Cui-qing, MA Li. The efficacy of pulmonary surfactant for pulmonary function in premature tension pneumothorax [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 146
-151
.
[6]
GAO Xiao-hui, MAO Jian. Clinical features of non-oliguric hyperkalemia in extremely low birth weight infants [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 152
-158
.
[7]
XIA Yao-fang, YANG Juan , TIAN Bao-li, et al. Value of amplitude-integrated electroencephalography in monitoring acute period of neonatal bilirubin encephalopathy and prognostic assessment [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 159
-163
.
[8]
WANG Li-rong, SUN Xiao-yan, ZHU Ruo-xin, et al. Epidemiological investigation and analysis of women aged 40-55 years old with osteoporosis in Gansu province [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 164
-167
.
[9]
CHEN Ru-yue, SHEN Yun-yan, CHEN Qing , et al. Five cases about Henoch-Schönlein purpura complicated with central nervous system injury in children and literatures review [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 168
-171
.
[10]
ZHANG Ai-run, FANG Xiao-yi. Lung function testing of bronchopulmonary dysplasia for infants and children [J]. Journal of Developmental Medicine(Electronic Version), 2017, 5(3): 172
-176
.
Viewed
Full text
Abstract
Cited
Shared
Discussed