发育医学电子杂志 2019, Vol. 7 Issue (1): 51-54, 59 DOI: 10.3969/j.issn.2095-5340.2019.01.012 |
围产医学
综述
|新生儿
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新生儿早发型败血症诊断方法的研究进展 |
张智源 林霓阳 房晓祎 |
1. 汕头大学医学院第一附属医院 新生儿科,广东 汕头 515041;2. 中山大学附属第七医院 新生儿科,广东 深圳 518107 |
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Advances in the diagnosis methods of early onset sepsis in neonates |
ZHANG Zhi-yuan LIN Ni-yang FANG Xiao-yi |
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摘要 新生儿败血症是目前导致新生儿死亡的主要原因之一[1]。虽然我国在 2003 年修订了相关指南[2]来指导临床医生进行诊断,但目前诊断的金标准仍然依赖于传统血培养结果。临床上存在多种因素干扰血培养的结果,包括新生儿的血量少、存在低或间歇性菌血症以及母亲产前使用抗生素等,都给临床医生的诊断带来困难与挑战[3-4]。同时,新生儿感染的临床表现存在较大差异,对疑似败血症的患儿使用过度的、不必要的经验性抗生素治疗,将会导致抗生素耐药性的产生。因此,需要精确和敏感的诊断工具来帮助早期诊断新生儿败血症。本文总结目前临床上常用的新生儿败血症诊断方法,并重点介绍分子生物学方法诊断新生儿感染及抗生素耐药性基因检测的相关研究进展。
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关键词:
font-family:宋体
font-size:14px
新生儿')" href="#">">新生儿
败血症
诊断方法
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收稿日期: 2018-04-04
出版日期: 2019-01-30
发布日期: 2019-02-02
期的出版日期: 2019-01-30
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基金资助: 广东省高水平大学重点学科建设(2016003) |
通讯作者:
林霓阳 http://z.xywy.com/zhuanjia-stuh-erke-linniyang.htm 房晓祎
E-mail: linniyang@126.com, judyfangxy@126.com
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