Clinical characteristic analysis of respiratory syncytial virus combined with influenza A virus infection in children
SUN Hai-bin, LI Ya-wen, GUO Yi, et al
1.Department of Neonatology, Wuxi Children’s Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214023, China; 2.Department of Pediatrics, the Second People’s Hospital of Wuxi Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, China)
Abstract: 【Abstract】 Objective To investigate the clinical characteristics of respiratory syncytial virus(RSV) combined with influenza A virus (inf-A) infection. Methods Sixty-one children whose age were less than 5 years old were selected from the Second People's Hospital of Wuxi from January 2010 to December 2016. Thirty-one cases who were infected by RSV and inf-A were studied as MIX group. Thirty RSV-infected children were selected as RSV group. The clinical characteristics of the two groups were retrospectively analyzed and compared. Results The average age and incidence of fever, vomiting, and dyspnea in the MIX group were higher than that in RSV group, with statistically significant differences (P﹤0.01 or P﹤0.05）. The incidence of cough was significantly lower in the MIX group than that in the RSV group(P﹤0.05). Patients of MIX group were more prone to develop severe pneumonia and myocardial injury(P﹤0.05). The rate of intravenous glucocorticoids in the MIX group was higher, and the hospital stay was longer than that in the RSV group. There were all statistical significance (P﹤0.05 or P﹤0.01). The proportion of children with CRP﹥40 mg/L in MIX group was higher than that in the RSV group, with statistical significance (P﹤0.05).Conclusion Infection mixed with RSV and inf-A is prone to occur in the older children, which is more prone to manifests as fever, vomiting, diarrhea, dyspnea and other symptoms, especially severe pneumonia.
2019, Vol. 7 
